Featured

• Dogs Suppress a Pivotal Function in the Food Webs of Sandy Beaches.
• The White House Conference on Hunger, Nutrition and Health Is an Opportunity for Transformational Change.
• Improved Growth and High Inheritance of Melanocortin-4 Receptor (mc4r) Mutation in CRISPR/Cas-9 Gene-Edited Channel Catfish, Ictalurus punctatus.
• RCT: Comparative Dietary Effectiveness of a Modified Government-Recommended Diet with Avoidance of Ultra-Processed Foods on Weight and Metabolic Management in Children and Adolescents.

Headline vs Study

• Headline: “Astonishing” Effects of Grape Consumption and “Remarkable” Impacts on Health and Lifespans.
• Study: Grape Powder (Not Grapes) Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity... In Female Mice.
• Study: Behavioral and Genetic Changes of Grape Powder (Not Grapes)... In Female Mice.
• Study: Grape Powder (Not Grapes) Modifies Hepatic and Urinary Metabolite Profiles... In Female Mice.

Contrary or Null Findings

• No Significant Weight or BMI Changes in Adults with Obesity Initiating Medical Marijuana Treatment for Other Medical Conditions.
• Meta-Analysis: No Significant Effect of Prevention Efforts on BMI-Related Measures.
• "No significant pooled IIDs [interindividual differences in effects] were found for aerobic exercise nor resistance training demonstrating that there is currently a lack of convincing evidence to support the notion that true IIDs exist for the anxiolytic effects of exercise among adults with anxiety- and stress-related disorders."
• Risk of Postoperative Stiffness Following Multiligamentous Knee Injury Surgery Is Not Affected by Obesity: A Multicenter Study.
• "Contrary to expectations, we saw no differences in FFA or uric acid levels between control and mitotane birds, but RU486 temporarily decreased stress-induced uric acid levels."
• RCT: "Contrary to previous thinking, the use of elastic bands around the forefeet during squats can elicit increased myoelectric activity of hip muscles, with a magnitude often greater than when the band is placed around the thigh segments."
• RCT: "VO2max was unaffected by 6 months of daily Calanus oil supplementation in healthy, physically fit, normal to overweight men and women between 30 and 50 years old."
• RCT: "The often reported acute increase in BP after caffeine supplementation could not be confirmed in this cohort of normotensive young adults."
• Meta-Analysis of RCTs: No Significant Difference in Benefits of Low-Carbohydrate Diets Versus Low-Fat Diets on Metabolic Risk Factors in Adults with Overweight and Obesity at 24 Months.
• RCT: A Pragmatic Low Carbohydrate Diet Intervention Changes Neither Carbohydrate Consumption nor Glycemia in Adolescents and Young Adults with Type 1 Diabetes.

Basic

• Ceramide Metabolism Associated with Chronic Dietary Nutrient Surplus and Diminished Insulin Sensitivity in the Liver, Muscle, and Adipose Tissue of Cattle.
• Glucagon Receptor Signaling at White Adipose Tissue Does Not Regulate Lipolysis.
• Short-Term High-Fat Diet Consumption Increases Body Weight and Body Adiposity and Alters Brain Stem Taste Information Processing in Rats.
• Mitochondrial Fission in Hepatocytes as a Potential Therapeutic Target for Nonalcoholic Steatohepatitis.
• Of Mice and Men: Considerations on Adipose Tissue Physiology in Animal Models of Obesity and Human Studies.

Scientific Rigor & Scholarly Dialogue

• “Holden Thorp, the Editor in Chief of … [Science], Says It’s Time to Improve the Process of Correcting the Scientific Record.”.
• Exploratory Hypothesis Tests Can Be More Compelling Than Confirmatory Hypothesis Tests.
• Retraction: Single Joint Exercises Do Not Provide Benefits in Performance and Anthropometric Changes in Recreational Bodybuilders.
• High-Profile Obesity Research Funded by Singapore Cited for Fraud.
• Re-Analysis and Additional Information Needed to Inform Conclusions. Comment on Halenova et al. Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats. Molecules 2020, 25, 23.

Clinical

• Obesity Paradox in Coronary Thrombus Burden of Patients with Acute Coronary Syndrome.
• Signaling Pathways in Obesity: Mechanisms and Therapeutic Interventions.
• Associations of BMI, Fasting Insulin, and Inflammation with Mortality: A Prospective Cohort Study.

Children and Adolescents

• Hair Glucocorticoid Concentration, Self-Perceived Stress and Their Associations with Cardiometabolic Risk Markers in Swedish Adolescents.
• Metabolic and Morphological Profile in Skeletal Muscle of Healthy Boys and Girls.
• Meta-Analysis: Association between Sleep Duration and Early Pubertal Timing in Children and Adolescents.

Surgery

• Association between Neighborhood Food Environment and Bariatric Surgery Outcomes.
• Human Gut Microbiota After Bariatric Surgery Alters Intestinal Morphology and Glucose Absorption in Mice Independently of Obesity.
• Association of Insurance Coverage with Adoption of Sleeve Gastrectomy vs Gastric Bypass for Patients Undergoing Bariatric Surgery.
• Examination of Elective Bariatric Surgery Rates Before and After US Affordable Care Act Medicaid Expansion.

Drugs

• Influence of Obesity on Blood Pressure Responses to Antihypertensive Drug Therapy in an Urban Hypertension Specialty Clinic.
• Discovery of a Novel Anti-Obesity Meroterpenoid Agent Targeted Subcutaneous Adipose Tissue.
• Formulation and Evaluation of Orlistat Loaded Microsponges for the Treatment of Obesity.
• Systematic Review: Effect of Semaglutide and Liraglutide in Individuals with Obesity or Overweight Without Diabetes.

Food & Diet

• The Ecuadorian School Food Environment: Association with Healthy and Unhealthy Food and Beverage Consumption and BMI.
• High-Dimensionality Reduction Clustering of Complex Carbohydrates to Study Lung Cancer Metabolic Heterogeneity.
• Review: Scoping Review and Evidence Map on the Relationship between Exposure to Dietary Sweetness and Body Weight-Related Outcomes in Adults.
• Dietary Total Antioxidant Capacity in Relation to Metabolic Health Status in Adolescents with Overweight and Obesity.

Caloric and Dietary Restriction

• Network Meta-Analysis: Comparative Effectiveness of a Low-Calorie Diet Combined with Acupuncture, Cognitive Behavioral Therapy, Meal Replacements, or Exercise for Obesity over Different Intervention Periods.
• Cumulative Consumption of Sulfur Amino Acids and Risk of Diabetes: A Prospective Cohort Study.
• The Protective Effect of Intermittent Fasting and Physical Exercise on Obesity Through Changes in Muscle Diameter.

Exercise & Physical Activity

• Review: The Role of Exercise-Induced Myokines in Promoting Angiogenesis.
• Meta-analysis: Effects of Three Modes of Physical Activity on Physical Fitness and Hematological Parameters in Older People with Sarcopenic Obesity.
• Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults.

Economics & Sociology

• Spatial Analysis of Neighborhood Vitality Determinants on Physical Activity: A Case Study of Chicago.
• Preprint: What Does the MacArthur Scale of Subjective Social Status Measure? Separating Economic Circumstances and Social Status to Predict Health.
• RCT: Exploring the Effects of Added Sugar Labels on Food Purchasing Behaviour in Australian Parents.

Epidemiology

• Multi-Sectoral Data Linkages to Explore Associations between the Built Environment and BMI.
• How Do the Home Food Environment, Parenting Practices, Health Beliefs, and Screen Time Affect the Weight Status of European Children?: FEEL4DIABETES-STUDY.
• Exploring the Intersectionality of Family SES and Gender with Psychosocial, Behavioural and Environmental Correlates of Physical Activity in Dutch Adolescents: A Cross-Sectional Study.

Psychology & Neuroscience

• The Association between Sleeping Behavior, Obesity, Psychological Depression, and Eating Habits Among Adolescents in the Emirate of Abu Dhabi–United Arab Emirates.
• RCT: Effects of an Exercise Program on Brain Health Outcomes for Children with Overweight or Obesity.
• Exposure to a Hypercaloric Diet Produces Long Lasting Changes in Motivation.

Equity and Disparities

• Adherence to the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and Obesity-Related Cancer Risk and Mortality in Black and Latina Women's Health Initiative Participants.
• Variable Impacts on Reproductive Energetics May Render Oviparous Squamates More Vulnerable to Climate Warming Than Viviparous Species.
• Systematic Review: Dietary Transitions and Health Outcomes in Four Populations.

Stigma

• Changes in Weight Bias After Simulation in Pre-License Baccalaureate Nursing Students.
• Dissertation: Assessing Weight Bias Among Healthcare Professionals: Creation and Validation of an Instrument.
• Legal Evolution of a Law Against Weight Discrimination in the United States: A Focus on Massachusetts.

Policy Related

• Addressing American Obesity: A Policy Proposal.
• Review: Effectiveness of School-Based Nutrition Intervention Components on Fruit and Vegetable Intake and Nutrition Knowledge in Children Aged 4–12 Years Old.
• The Corporate Influence on Food Charity and Aid: The “Hunger Industrial Complex” and the Death of Welfare.
• 'What Do Doctors Think They Need to Know About Nutrition?’—a Qualitative Study of Doctors with Formal Nutrition Training.
• RCT: Perceptions of Two Energy Drink Health Warning Labels.

Intergenerational Effects

• Maternal and Fetal Factors Affecting Cord Plasma Leptin and Adiponectin Levels and Their Ratio in Preterm and Term Newborns: New Insight on Fetal Origins of Metabolic Dysfunction.
• Relationships between Intrauterine Fetal Growth Trajectories and Markers of Adiposity and Inflammation in Young Adults.
• Association between Fetal Abdominal Growth Trajectories, Maternal Metabolite Signatures Early in Pregnancy, and Childhood Growth and Adiposity: Prospective Observational Multinational INTERBIO-21st Fetal Study.
• Maternal Pre-Pregnancy BMI and Mental Health Problems in Early Adolescents from the 2004 Pelotas Birth Cohort.

Ecology, Evolution, & Energetics

• Individual Variation in Heat Substitution: Is Activity in the Cold Energetically Cheaper for Some Individuals Than Others?
• Metabolic Scaling Is the Product of Life-History Optimization.

Methods

• Correlation between Subcutaneous Adipose Tissue of the Head and BMI: Implications for Functional Neuroimaging.
• Cluster Randomised Trials with a Binary Outcome and a Small Number of Clusters: Comparison of Individual and Cluster Level Analysis Method.

Commentary

• When Is a Calorie Not a Calorie?
• Want to Lower Your Risk of Early Death? 3 Activities are Most Beneficial, Study Says.
• "No randomized controlled trials have been conducted on the guidelines put forth by those in the Fertility Diet book."
• A New Combination Therapy Hits the Mark.
• Physical Activity May Have a Stronger Role Than Genes in Longevity.
• Can You Be Healthy and Have Obesity? Not Really, Says Major Study.
• Can the White House Nutrition Conference Help?
• Moisture Meter Tackles Mycotoxins in Ghana's Grains.

General

• Substance Use Reaches 30-Year Low Among Indiana Youth, Survey Finds.
• Preprint: Bootstrap Inference in the Presence of Bias.
• A Metabolite Produced by Gut Microbes Represses Phage Infections in Vibrio cholerae.
• “In a Week, We Can Tell If Something Slows Aging”.
• Epigenetic ‘Clocks’ Predict Animals’ True Biological Age.
• Socioeconomic Impacts on Andean Adolescents’ Growth: Variation between Households, between Communities, and over Time.
• Beneficial Effects of Apigenin on the Transgenic Drosophila Model of Alzheimer's Disease.
• Hiding Chocolate Stashes or Amazon Purchases from a Partner? ‘Guilty’ Purchases May Have Benefits.

Announcements

• Indiana University Bloomington Recognized Nationally for Commitment to LGBTQ+ Students.
• IU Food Institute Open House.
• Nutrition 2022: Food for the Brain: Bridging the Nutrition and Neurology Scientific Communities.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.