Featured

• "Across measures of weight status, physical activity/sedentary behaviour, and nutrition, the effects reported in scaled‐up interventions were typically 75% or less of the effects reported in pre–scale‐up efficacy trials."
• Validation of Sensor-Based Food Intake Detection By Multicamera Video Observation in an Unconstrained Environment.
• Targeting Senescent Cells Alleviates Obesity-induced Metabolic Dysfunction.

Headline vs Study

• Headline: Keto Diet Not Effective, Causes Blood Sugar Problems in Women.
• Press-release: Females Respond Poorly to Ketogenic Weight Loss Diet in an Animal Model.
• Headline: Snorting Sugar Could Help Fight Lung Disease, Study Says.
• Study: Study of Mouse Lung Macrophages and Inflammation. No Sugar Snorting.

Contrary or Null Findings

• RCT: "Phentermine did not improve on large weight losses achieved with liraglutide alone."
• RCT: "We found no evidence that a pre-conception lifestyle intervention improved female wellbeing five years after randomization." (pdf)
• "While dual burdens of anemia, stunting, and underweight are prevalent, there is no evidence of clustering of overweight with other forms of malnutrition in India."
• "An obesity prevention intervention integrating brief provider counseling and parent‐targeted phone counseling did not impact 12 and 24‐month BMI status overall but did have a significant impact on BMI in girls."
• "Contrary to popular belief, results of this review suggest that the use of natural supplements for weight loss are unlikely to contribute to meaningful weight loss and in some cases may contribute to harm."
• "In contrast to young mice, advanced-age mice on [Western-type Diet] did not show a higher body weight or adipose tissue masses."

Basic

• Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.
• Review: Extrinsic and Intrinsic Immunometabolism Converge: Perspectives on Future Research and Therapeutic Development for Obesity.
• Compensation for Cold-induced Thermogenesis During Weight Loss Maintenance and Regain in Mice.
• Adipose Lipocalin 2 Overexpression Protects Against Age-Related Decline in Thermogenic Function of Adipose Tissue and Metabolic Deterioration.
• Role of Arginase 2 in Systemic Metabolic Activity and Adipose Tissue Fatty Acid Metabolism in Diet-Induced Obese Mice.
• Involvement of Gastrin-Releasing Peptide Receptor in the Regulation of Adipocyte Differentiation in 3T3-L1 Cells.

Scientific Rigor & Scholarly Dialogue

• Preprint: Improving the Scientific Rigor of Nutritional Recommendations for Adults with Type 2 Diabetes: a Comprehensive Review of the American Diabetes Association Guidelines Recommended Eating Patterns.
• Letter: BMI as a Potential Confounder for Oncological Outcomes Following Autologous Fat Transfer.
• Reply: BMI as a Potential Confounder for Oncological Outcomes Following Autologous Fat Transfer.
• Article: Associations of Obesity and Circulating Insulin and Glucose with Breast Cancer Risk: A Mendelian Randomization Analysis.
• Letter: Regarding Article, “Associations of Obesity and Circulating Insulin and Glucose with Breast Cancer Risk: A Mendelian Randomization Analysis”.
• Letter: Letter to the Editor on ‘Dietary Patterns and Endometrial Cancer: A Meta-analysis’.
• Reply: Reply to Alizadeh’s Letter to the Editor on ‘Dietary Patterns and Endometrial Cancer: A Meta-analysis’.

Clinical

• Primary Care Interventions for Obesity: Review of the Evidence.
• RCT: The Effects of Diet-induced Weight Loss on Asthma Control and Quality of Life in Obese Adults with Asthma.
• Comparison of Surgical Versus Diet‐induced Weight Loss on Appetite Regulation and Metabolic Health Outcomes.

Children and Adolescents

• Assessing the Agreement of 5 Ideal Body Weight Calculations for Selecting Medication Dosages for Children with Obesity.
• Differential Genome-wide DNA Methylation Patterns in Childhood Obesity.
• Assessment of Parents’ Preferences for Incentives to Promote Engagement in Family-Based Childhood Obesity Treatment.
• RCT: Impact of a Childcare Food Service Intervention on Child Dietary Intake in Care.
• Systematic Review: Biomechanical Characteristics of Walking in Children and Adolescents with Overweight/Obesity: Possible Implications for the Development of Musculoskeletal Disorders.

Surgery

• Consequences of Bariatric Surgery on Outcomes in Rheumatic Diseases.
• Operative Morbidity of Laparoscopic Sleeve Gastrectomy in Subjects Older than Age 65.
• Gastric Bypass Versus Sleeve Gastrectomy: Patient Selection and Short-term Outcome of 47,101 Primary Operations From the Swedish, Norwegian, and Dutch National Quality Registries.
• Metabolic Surgery for Hypertension in Patients with Obesity.

Drugs

• RCT: Pharmacokinetics of Anakinra in Subjects of Heavier Versus Lighter Body Weights.
• RCT: Rituximab Maintenance Overcomes the Negative Prognostic Factor of Obesity in CLL: Subgroup Analysis of the International Randomized AGMT CLL‐8a Mabtenance Trial.
• Liraglutide Modulates Adipokine Expression During Adipogenesis, Ameliorating Obesity, and Polycystic Ovary Syndrome in Mice.
• RCT: Continuous Subcutaneous Insulin Infusion Versus Multiple Daily Injection Regimens in Children and Young People at Diagnosis of Type 1 Diabetes: Pragmatic RCT and Economic Evaluation.

Food & Diet

• Increased Hunger, Food Cravings, Food Reward, and Portion Size Selection After Sleep Curtailment in Women Without Obesity.
• Meta-analysis: The Effect of Liquid Meal Replacements on Cardiometabolic Risk Factors in Overweight/Obese Individuals with Type 2 Diabetes.
• Change in Plant-Based Diet Quality is Associated with Changes in Plasma Adiposity-Associated Biomarker Concentrations in Women.
• Review: The Influence of Meal Frequency and Timing on Health in Humans: The Role of Fasting.
• Within-person Compensation for Snack Energy By US Adults, NHANES 2007–2014.
• US Experts Reviewing Low-carb, Other Diets for Guidelines.

Caloric Restriction

• Intermittent Fasting Beneficial Effects on the Steatosis and Inflammation of the Liver in Mice Fed a High-fat or a High-fructose Diet.
• Review: Epigenetic Regulation of Metabolism and Inflammation By Calorie Restriction.
• Long‐term Caloric Restriction Ameliorates Deleterious Effects of Aging on White and Brown Adipose Tissue Plasticity.
• Six Weeks of Morning Fasting Causes Little Adaptation of Metabolic or Appetite Responses to Feeding in Adults with Obesity.

Exercise & Physical Activity

• Percentage of Adults Who Met Federal Guidelines for Aerobic Physical Activity Through Leisure-Time Activity,* By Race/Ethnicity — National Health Interview Survey,† 2008–2017.
• "Greater self‐reported overall physical fitness and its components are associated with less bodily, lumbar and sciatic pain, and reduced pain disability during pregnancy."
• Assessment of Maximal Fat Oxidation During Exercise: A Systematic Review.
• Associations Between Walk Score and Objective Measures of Physical Activity in Urban Overweight and Obese Women.
• The Association Between Negative Affect and Physical Activity Among Adults in a Behavioral Weight Loss Treatment.

Economics & Sociology

• A Multilevel Study of Neighborhood Disadvantage, Individual-socioeconomic Position, and BMI.
• Neighborhood Outdoor Play of White and Non-White Hispanic Children: Cultural Differences and Environmental Disparities.
• Cultivating Cultural Competence to Address Childhood Obesity in Ethnic Minority Youth.

Epidemiology

• Multivariate Analysis of Genome-wide Data to Identify Potential Pleiotropic Genes for Type 2 Diabetes, Obesity and Coronary Artery Disease Using MetaCCA.
• Race/Ethnicity, Obesity, and the Risk of Being Verbally Bullied: A National Multilevel Study.
• Visceral Obesity, but Not Central Obesity, is Associated with Cardiac Remodeling in Subjects with Suspected Metabolic Syndrome.
• Geographical Variation in the Prevalence of Obesity and Metabolic Syndrome Among US Adolescents.

Psychology & Neuroscience

• Effects of Mood Induction Using Movie Watching on Food Intake and Hormone Levels.
• Motivational Interviewing and Home Visits to Improve Health Behaviors and Reduce Childhood Obesity: A Pilot Study.
• Implementation of a Virtual Patient-centered Weight Loss Maintenance Behavior Competency Assessment in Adults with Obesity.

Equity and Disparities

• BMI Across the Life-Course: Emergence of Race By Sex Disparities in Early Childhood.
• Socioeconomic Inequalities in Obesity: Modelling Future Trends in Australia.

Stigma

• Moral Discourse in General Practitioners’ Accounts of Obesity Communication.
• Psychosocial Stress and Overweight and Obesity: Findings From the Chicago Community Adult Health Study.
• Validation of the Two-Factor Weight Bias Internalization Scale.
• Relationship Between Overweight Identification, Dieting Behaviors, and Body Measurements.
• Blatant Dehumanization of People with Obesity.

Intergenerational Effects

• Parent-Perceived Stress and Its Association with Children’s Weight and Obesity-Related Behaviors.
• Associations of Pre-Pregnancy BMI, Gestational Weight Gain and Maternal Parity with the Trajectory of Weight in Early Childhood: A Prospective Cohort Study.
• Maternal BMI and Risk of Neonatal Adverse Outcomes in China: A Systematic Review and Meta-analysis.

Ecology, Evolution, & Energetics

• Food Sharing and Affiliation: An Experimental and Longitudinal Study in Cockatiels (Nymphicus Hollandicus).
• The Relationship Between Housing Types and Metabolic and Weight Phenotypes: A Nationwide Survey.

Methods

• Machine Learning-Based Method for Obesity Risk Evaluation Using Single-Nucleotide Polymorphisms Derived From Next-Generation Sequencing.
• BMI vs Deuterium Dilution Method for Establishing Childhood Obesity Prevalence, Ghana, Kenya, Mauritius, Morocco, Namibia, Senegal, Tunisia and United Republic of Tanzania.
• The Causal Association Between Obesity and Stillbirth: Strengths and Limitations of the Consecutive Pregnancies Approach.

Mathematical and Quantitative

• Meta-regression: Associations Between the Rate, Amount, and Composition of Weight Loss as Predictors of Spontaneous Weight Regain in Adults Achieving Clinically Significant Weight Loss.
• Application of mathematical models in the management of obesity during pregnancy and the postpartum period in reproductive age women.

Commentary

• Overeating and Food Position Memory Halted By Neural Stimulation.
• Public Health Messages that Help or Hurt.
• Take Your Vegetables By Prescription?
• Communicating About Risk in a Food-Obsessed World—Reprised.
• Most Cats and Dogs in the US are Overweight, New Study Reveals.
• A Doctor’s Advice on Weight: Useful or Not?

General

• The Lost History of One of the World’s Strangest Science Experiments.
• Central Macular Thickness in Diabetic Patients: A Sex-based Analysis.
• Figure Errors, Sloppy Science, and Fraud: Keeping Eyes on Your Data.
• Three Research-based Lessons to Improve Your Mentoring.
• Scientific Integrity and Data Accuracy.
• University Fights Restrictive Indiana Law on Fetal Tissue Research.
• "Although single-meal studies clearly show an increase in iron bioavailability from dephytinization of cereals, medium-term consumption of reduced phytate bread under free-living conditions suggests that this strategy does not work to improve iron status in healthy women of reproductive age."
• FTC Hits Predatory Scientific Publisher with a $50 Million Fine.

Video & Audio

• Audio: Science vs - Fasting Diets: What's the Skinny?
• E30: Christina Roberto on Food Labeling in Guatemala and Soda Taxes in Philly.
• Video: Weight Gain at Menopause.

Announcements

• Health Equity Advocate Shiriki Kumanyika Receives 2019 Elizabeth Fries Health Education Award.
• Steven Austad, Ph.D., and UAB Postdoctoral Fellow in Longevity Research Jessica Hoffman, Ph.D., Have Won the George C. Williams Prize From the International Society for Evolution, Medicine and Public Health, or ISEMPH.
• Book Reviews: Globe to Gut: Inside Big Food.
• Obesity Research the Focus of Indiana CTSI Spring Retreat at IU Bloomington.
• Bloomington Rated 5th Best U.S. City in Which to Raise a Family.
• Indiana is getting "Real" about the food they serve: BTN LiveBIG.
• NORC of UAB Seeks Post-doctoral Fellows in Obesity Research.
• UAB Seeks Post-doctoral Fellows for Its AHA Strategically Focused Research Center– Obesity Network: Intergenerational Transmission of Obesity.
• Short Courses on Causal Inference and Mathematical Sciences in Obesity Research, Summer 2019.