Obesity and Energetics Offerings

Featured

• RCT: Effects of a Diabetes Prevention Program on Type 2 Diabetes Risk Factors and Quality of Life Among Latino Youths with Prediabetes.
• E4orf1 Prevents Progression of Fatty Liver Disease in Mice on High Fat Diet.
• Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor Initiation and Hepatocellular Carcinoma Prognosis.
• Variability in Energy Expenditure Is Much Greater in Males Than Females.

Headline vs Study

• Study: Timing of Daily Calorie Loading Affects Appetite and Hunger Responses Without Changes in Energy Metabolism in Healthy Subjects with Obesity.
• Headlines: PlumX Metrics Show Mostly Reasonable Headlines!

Contrary or Null Findings

• RCT: Front-Loading Calories Early in the Day Reduces Hunger but Does Not Affect Weight Loss.
• RCT: Seven-Month Wintertime Supplementation of 1200 IU Vitamin D Has No Effect on Hand Grip Strength in Young, Physically Active Males.
• RCT: One-Week L-Arginine Supplementation Had No Effect on 200m Freestyle Swimming Time Trial in Moderately-Trained Male Swimmers.
• RCT: No Evidence of Brown Adipose Tissue Activation After 24 Weeks of Supervised Exercise Training in Young Sedentary Adults.
• RCT: No Differential Effect of DASH Diet vs. DASH Diet Plus Physical Activity in Older Patients with Type 2 Diabetes and High Blood Pressure.
• "These findings, surprisingly, indicate that during substantial weight gain, an increase in small adipocytes (suggesting hyperplastic expansion) is associated with impaired (not improved) metabolic health outcomes, specifically visceral and ectopic fat accumulation."
• "Contrary to the belief that adult adipocytes are relatively static, we show that adipocytes are very dynamic, relying on actin-driven mechanical forces to execute LD extrusion and intercellular LD transfer processes."
• Calorie Restriction Has No Effect on Bone Marrow Tumour Burden in a Vk*MYC Transplant Model of Multiple Myeloma [in Mice].

Basic

• Obesity Aggravated Hippocampal-Dependent Cognitive Impairment After Sleeve Gastrectomy in C57/BL6J Mice Via SIRT1/CREB/BDNF Pathway.
• Fish Oil Supplementation of Rats Fed a High Fat Diet During Pregnancy Improves Offspring Insulin Sensitivity.
• Malnourishment Affects Gene Expression Along the Length of the Small Intestine.
• Exercise and Metformin Intervention Prevents Lipotoxicity-Induced Hepatocyte Apoptosis by Alleviating Oxidative and ER Stress and Activating the AMPK/Nrf2/HO-1 Signaling Pathway in db/db Mice.
• Influences of the Interactions of Genetic Variations of Seven Core Circadian Clock Genes with Lifestyle Factors on Metabolic Parameters.
• Excess Dietary Zinc Drives a Cushing's-Like Syndrome in Ovariectomized Mice – Implications for Postmenopausal Obesity.

Scientific Rigor & Scholarly Dialogue

• Registering Incredulity.
• Strengthening Causal Inference from RCTs of Complex Interventions.

Clinical

• Scoping Review: Peripartum Care of Persons with Obesity.
• Effect of a Lifestyle Intervention on Cardiometabolic Health Among Emerging Adults.
• Effectiveness of a Nurse-Led mHealth App to Prevent Excessive Gestational Weight Gain Among Women with Overweight and Obesity.
• Fat-To-Muscle Ratio as a Predictor for Dyslipidaemia in Transitional-Age Youth.

Children and Adolescents

• Prospective Cohort Study: Association between Key Family and Individual Factors and Obesity Status Among Youth.
• "The First Step to Changing Something": Addressing Latinx Childhood Obesity through Photovoice.
• Metabolic Impact of Infant Formulas in Young Infants. An Outlook from the Urine Metabolome.
• Improving Nutrition in the First 1000 Days in the United States: A Federal Perspective.
• Developmental Pathways Linking Obesity Risk and Early Puberty: The Thrifty Phenotype and Fetal Overnutrition Hypotheses.

Surgery

• Meta-Analysis: New Insights on the Association between Socioeconomic Status and Weight Loss After Bariatric Surgery.
• Can Serum Basal Cortisol Values Predict Successful Operations for Bariatric Surgery Patients?
• Trends in Adolescent Bariatric Procedures: A 15-Year Analysis of the National Inpatient Survey.

Drugs

• RCT: 8-Week Intranasal Oxytocin Administration in Adults with Obesity: Rationale, Study Design, and Methods.
• Anti-Obesity Carbonic Anhydrase Inhibitors: Challenges and Opportunities.

Food & Diet

• RCT: The Effect of Steamed Potato-Wheat Bread Intake on Weight, Lipids, Glucose, and Urinary Na +/K +.
• Meta-Analysis: Effect of Flavonoid Intake on Circulating Levels of Adiponectin and Leptin.
• Association of Nut Consumption with CVD Risk Factors in Young to Middle-Aged Adults.
• "Increase in dietary choline or betaine intake were longitudinally related to improvements in cardiometabolic parameters".

Caloric and Dietary Restriction

• RCT: Effects of Inulin Supplementation on Inflammatory Biomarkers and Clinical Symptoms of Women with Obesity and Depression on a Calorie-Restricted Diet.
• RCT: Effect of Mediterranean Diet and Mediterranean Diet Plus Calorie Restriction on Cognition, Lifestyle, and Cardiometabolic Health.
• Obesity-Associated Anxiety Is Prevalent Among College Students and Alleviated by Calorie Restriction.

Exercise & Physical Activity

• Hypoxic High-Intensity Interval Training in Individuals with Overweight and Obesity.
• Late Afternoon Vigorous Exercise Increases Post-Meal but Not Overnight Hypoglycemia in Adults with Type 1 Diabetes Managed with Automated Insulin Delivery.
• Effects of Weight-Bearing Vs. Non-Weight-Bearing Endurance Exercise on Reducing Body Fat and Inflammatory Markers in Females with Obesity.
• Myokines in Adolescents with Obesity During Aerobic Exercise.

Economics & Sociology

• Systematic Review: Cost-Effectiveness of Continuous Glucose Monitoring Compared to Self-Monitoring of Blood Glucose in Type 1 Diabetes.
• Longitudinal Exposure to Neighborhood Poverty and Obesity Risk in Emerging Adulthood.

Epidemiology

• Long-Term Trends in Obesity Prevalence by Socio-Economic Group in Five European Countries and the USA.
• Body Composition of the Upper Limb Associated with Hypertension, Hypercholesterolemia, and Diabetes.

Psychology & Neuroscience

• Systematic Review: Effects of Mirror Exposure on Behaviour in Individuals with Obesity.
• Investigating Psychological Variables for Technologies Promoting Physical Activity.

Equity and Disparities

• Review: Care of Gender Diverse Youth with Obesity.
• Black New Yorkers with Type 2 Diabetes: Afro-Caribbean Immigrants Have Lower BMI and Lower Waist Circumference Than African Americans.

Stigma

• Cross-Sectional: Internalised Weight Stigma Mediates Relationships between Perceived Weight Stigma And Psychosocial Correlates In Individuals Seeking Bariatric Surgery.
• Cross-Sectional & Mixed Methods: “Thin and Muscular”.
• Fat Stigma and Body Objectification: A Text Analysis Approach Using Social Media Content.
• How Is Physicians' Implicit Prejudice Against People with Obesity or Mental Illness Moderated by Specialty and Experience?

Policy Related

• Cluster RCT: The Efficacy of a Multi-Strategy Choice Architecture Intervention on Improving the Nutritional Quality of High School Students' Lunch Purchases from Online Canteens (Click & Crunch High Schools).
• Review: Food Governance for Better Access to Sustainable Diets.
• Time Preference and Nutrition Label Use: Evidence from China.
• An Evaluation of the 'Bottom-Up' Implementation of the Active at School! Programme in Quebec, Canada.
• Case Study Implementing Nutrition and Sustainability Policy Into Government Food Procurement.
• Obesity Disparities and Evaluation of Public Policy Interventions at the Local Level.

Intergenerational Effects

• Meta-Analysis: Associations of Timing of Maternal Smoking Cessation Before and During Pregnancy with Childhood Overweight and Obesity.
• Longitudinal Characterization of Determinants Associated with Obesogenic Growth Patterns in Early Childhood.
• Prenatal Exposure to Polybrominated Diphenyl Ethers and BMI Z-Scores from 5 to 14 years.
• Protective Effect of Prenatal Social Support on the Intergenerational Transmission of Obesity in Low-Income Hispanic Families.
• Human Placental Lipid Content and Lipid Metabolic Enzyme Abundance in Obesity and Across Gestation.
• Associations between Maternal Metabolic Parameters During Pregnancy and Fetal and Child Growth Trajectories from 20 Weeks' Gestation to 5 years of Age.

Ecology, Evolution, & Energetics

• Scoping Review: Evaluating the Human Capacity of Carrying Loads Without Costs.
• Review: Neuroendocrine MicroRNAs Linked to Energy Homeostasis: Future Therapeutic Potential.
• Novel Host Unmasks Heritable Variation in Plant Preference Within an Insect Population.
• The Evolving View of Thermogenic Fat and Its Implications in Cancer and Metabolic Diseases.

Methods

• Personalized Energy Expenditure Estimation: Visual Sensing Approach with Deep Learning.
• Issues Related to the Assessment of Energy Balance During Short-Term Over-, Under- and Refeeding in Normal Weight Men.
• Anthropometric Equations to Predict Visceral Adipose Tissue in European and American Youth.

Commentary

• Sarcopenia and Sarcopenic Obesity in Chronic Kidney Disease: Update on Prevalence, Outcomes, Risk Factors and Nutrition Treatment.
• Food Texture Trumps Food Processing in the Regulation of Energy Intake.
• Looking for Real Plants in a Plant-Based Diet.
• Can the White House Fix Food?
• Locked Into the Wrong Debate About Obesity.
• Off-Label Drugs for Obesity.
• Treating Obesity to Prevent Diabetes.
• Adolescents with Anorexia Nervosa or Atypical Anorexia Nervosa with Premorbid Overweight/Obesity: What Should We Do About Their Weight Loss?

General

• Pilot Study: Effect of Cocoa (Theobroma cacao L.) on Platelet Function Testing Profiles in Patients with Coronary Artery Disease.
• That’s a Lot to Process! Pitfalls of Popular Path Models.
• Does Constructing a Belief Distribution Truly Reduce Overconfidence?
• No Evidence That Mandatory Open Data Policies Increase Error Correction.
• An Empirical Bayes Approach to Improving Population-Specific Genetic Association Estimation by Leveraging Cross-Population Data.
• Sex-Specific Endocrine Regulation of Seasonal Aggression in Siberian Hamsters.
• Body Image and Health-Related Behaviors Among Fitspirit Participants.
• On the Importance of the Dynamics of Humour and Comedy for Constructionism and Reflexivity in Social Science Research Methodology.

Video & Audio

• Greater male variability in energy expenditure (accompanies "Featured" article "Variability in Energy Expenditure Is Much Greater in Males Than Females."

Announcements

• "IU Bloomington and Indiana University-Purdue University-Indianapolis (IUPUI) received the only national award that honors individual institutions for being outstanding examples of universities committed to making diversity and inclusion a top priority across their campuses."
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.
• USDA Funds IU-Led Research Team to Develop Disease-Resistant Wheat.

Featured

• RCT: Effects of a Whole Food Diet on Immune Function and Inflammatory Phenotype in Healthy Dogs.
• Antipsychotic-Induced Weight Gain and Metabolic Effects Show Diurnal Dependence and are Reversible with Time Restricted Feeding.
• Medications for Obesity Management: Effectiveness and Value - Evidence Report. (pdf)
• Interview with Dr. Sara Bleich, Director of Nutrition Security and Health Equity for the U.S. Department of Agriculture’s (USDA) Food and Nutrition Service.

Headline vs Study

• Headline: Mom and Dad Were Right: New Study Shows Just How Important Breakfast Really Is. It Turns Out Where Kids Eat Breakfast Matters a Whole Lot, Too.
• Study: Cross-sectional correlation of skipping breakfast or eating breakfast out of home and psychosocial behavioral problems in Spanish children. NOT consuming "coffee, milk, tea, chocolate, cocoa, yogurt, etc." or "bread, toast, cookies, pastries, etc." for breakfast was related to greater odds of psychosocial behavioural problems, too!

Contrary or Null Findings

• "Contrary to prior research, the intake of salty snacks and alcoholic beverages dropped by 3.3% and 2.8%, respectively, during the first lockdown."
• "Contrary to our hypothesis, birth related factors (e.g., low birth weight, preterm birth and exclusive breastfeeding until 6 months of age) are not associated with physical inactivity."
• "Contrary to reports suggesting levels of MGL [monoacylglycerol lipase] should be attenuated, our results revealed a marked increase of both targets in the gastrointestinal tract...in a Murine Model of Obesity."
• "We found, contrary to what is reported to occur in adults, that pre-operative percentage loss of adipose tissue in subcutaneous, visceral, and intermuscular compartments was similar to the post-operative percentage loss of corresponding adipose tissue compartments in adolescents 12 to 26 weeks after sleeve gastrectomy."
• "Contrary to predictions, females with higher body condition indices produced yolks that grew more slowly, and yolks from supplemented birds grew more slowly than controls. These results indicate that females can modulate the rate of yolk incorporation into developing follicles, and that an energy balance that is too high may not be optimal for the fast growth of developing ovarian follicles."
• Meta-Analysis of RCTs: No Significant "Effects of exercise training in hypoxia versus normoxia on fat-reducing in overweight and/or obese adults."
• RCT: "this trial did not provide evidence for effects of a single dose of inorganic nitrate on 4 h vascular endothelial function in abdominally obese men."
• RCT: No Significant "Efficacy of Exercise Training for Cutaneous Microvascular Reactivity in the Foot in People with Diabetes and Obesity."

Basic

• Sclerostin Aggravates Insulin Signaling in Skeletal Muscle and Hepatic Steatosis Via Upregulation of ER Stress by MTOR-Mediated Inhibition of Autophagy Under Hyperlipidemic Conditions.
• Regulation of Metabolic Health by Dietary Histidine in Mice.
• Vitamin D3 Affects Browning of White Adipocytes by Regulating Autophagy Via PI3K/Akt/mTOR/p53 Signaling in Vitro and in Vivo.
• The Influence of Parental High-Fat High-Sugar Diet on the Gut-Brain Axis in Male Offspring.
• Dietary Lipids Inhibit Mitochondria Transfer to Macrophages to Divert Adipocyte-Derived Mitochondria Into the Blood.
• Extracellular Vesicles Mediate the Communication of Adipose Tissue with Brain and Promote Cognitive Impairment Associated with Insulin Resistance.

Scientific Rigor & Scholarly Dialogue

• Proposal of a Selection Protocol for Replication of Studies in Sports and Exercise Science.
• Confidence Intervals and Smallest Worthwhile Change are Not a Panacea: A Response to the International Society of Physiotherapy Journal Editors.

Clinical

• RCT: Masticatory Behavior Change with a Wearable Chewing Counter.
• RCT: No Evidence of Brown Adipose Tissue Activation After 24 Weeks of Supervised Exercise Training in Young Sedentary Adults in the ACTIBATE Study.
• RCT: Colonic and Peripheral Blood Short-Chain Fatty Acids Modulates the Blood B- and T-Cell Compartments in Healthy Humans.

Children and Adolescents

• Meta-Analysis: Effects of Computer-Based Interventions on Food Consumption and Anthropometric Parameters of Adolescents.
• Risk Factors Associated with Postoperative Obesity in Childhood-Onset Craniopharyngioma Patients: A Case-Control Study.
• Association of Maternal Psychological Distress with Children with Overweight/obesity in Ethiopia.
• Metabolic Syndromes in School-Age Children with Overweight/Obesity.
• Maternal-Child Overweight Relationship, Assessment of Maternal Perception of Child Weight Status and Feeding Behaviours.

Surgery

• Review: Bile Acids, Gut Microbiota and Metabolic Surgery.
• RCT: Paragastric Autonomic Neural Blockade to Prevent Early Visceral Pain and Associated Symptoms After Laparoscopic Sleeve Gastrectomy.
• Review: Nutritional Management and Role of Multidisciplinary Follow-Up After Endoscopic Bariatric Treatment for Obesity.
• 24-Month Follow-Up of RCT of Guided-Self-Help for Loss-Of-Control Eating After Bariatric Surgery.

Drugs

• Diabetes Drug Results in Substantial Weight Loss in People with Obesity, Study Finds.
• Biomaterial-Based Therapeutic Strategies for Obesity and Its Comorbidities.
• Macrophage Membrane-Camouflaged Lipoprotein Nanoparticles for Effective Obesity Treatment Based on a Sustainable Self-Reinforcement Strategy.
• Review: Drug Dosing in Children with Obesity.

Food & Diet

• Associations of Eating Speed with Fat Distribution and Body Shape Vary in Different Age Groups and Obesity Status.
• Association of Lifelines Diet Score (LLDS) and Metabolically Unhealthy Overweight/Obesity Phenotypes in Women: A Cross-Sectional Study.
• Dietary Carbohydrates: Pathogenesis and Potential Therapeutic Targets to Obesity-Associated Metabolic Syndrome.
• High-Refined Carbohydrate Diet Alters Different Metabolic Functions in Female Rats.
• Meta-Analysis: Human Milk Lipid Profiles around the World.
• A Scoping Review of the Environmental Impacts and Nutrient Composition of Plant-Based Milks.
• Systematic Review: Should a Bedtime Snack Be Used to Treat Hyperglycemia in Type 2 Diabetes?

Caloric and Dietary Restriction

• Are Methods of Estimating Fat-Free Mass Loss with Energy-Restricted Diets Accurate?
• RCT: Preoperative Short-Term Restriction of Sulfur-Containing Amino Acid Intake for Prevention of Acute Kidney Injury After Cardiac Surgery.
• Competing Paradigms of Obesity Pathogenesis: Energy Balance Versus Carbohydrate-Insulin Models.

Exercise & Physical Activity

• One-Week L-Arginine Supplementation Had No Effect on 200m Freestyle Swimming Time Trial in Moderately-Trained Male Swimmers.
• Meta-Analysis: Physical Activity Participation and Physical Aggression in Children and Adolescents.
• Preprint: A Multicomponent Intervention Program Modifies the Cluster of Insulin Biomarkers, Body Composition, Physical Fitness, and Behaviors in Adolescents with Overweight or Obesity: A Network Perspective.

Economics & Sociology

• The Optics of Weight: Expert Perspectives from the Panopticon and Synopticon.
• Unraveling the Meaning of Weight Misperception in a Sample of College Students: Unaware or Body Satisfied?
• Association of Neighborhood Economic Trajectories with Changes in Weight Status Among Black and White Adults in the Southeastern US.

Epidemiology

• BMI and Physical Frailty Among Older Mexican Americans: Findings from an 18-Year Follow Up.
• Analysis of Gestational Weight Gain During the COVID-19 Pandemic in the US.

Psychology & Neuroscience

• The Impact of Social Rhythm and Sleep Disruptions on Waist Circumference After Job Loss: A Prospective 18-Month Study.
• The Goal Conflict Model: A Theory of the Hedonic Regulation of Eating Behavior.
• Is Time-Restricted Eating a Robust Eating Regimen During Periods of Disruptions in Daily Life? A Qualitative Study of Perspectives of People with Overweight During COVID-19.
• Stress and Eating Responses in Adolescent Females Predisposed to Obesity: A Pilot and Feasibility Study.

Equity and Disparities

• Socioeconomic Inequalities in the Consumption of Fruit and Vegetables in Peru between 2014 and 2019.
• Racial Disparities in Neighborhood and Household Socioeconomic Disadvantage Predict Postpartum Weight Retention.
• Surgery for the Treatment of Obesity in Children and Adolescents.
• The Portuguese Economic Crisis Is Associated with Socioeconomic and Sex Disparities on Children's Health-Related Behaviors and Obesity: A Cross-Sectional Study.
• Obesity in Women with Asthma: Baseline Disadvantage Plus Greater Small-Airway Responsiveness.

Stigma

• Bullying Victimization, Obesity, Sleep Quality, and Gender: The Moderating Effects of Academic Achievement.
• Preprint: Trends in the Relationship between Suicide Behaviors and Obesity Among Adolescents in the United States from 1999-2019.

Policy Related

• Commentary: Interdisciplinary Insights on the Future of Food Systems Research: Perspectives from the Next Generation of Research Leaders.
• Medicaid Expansion: The Impact of Health Policy on Bariatric Surgery.
• Cloudy with a Chance of Munchies: Assessing the Impact of Recreational Marijuana Legalization on Obesity.
• Focus Group Study: Adolescents’ Perspectives on Soft Drinks After the Introduction of the UK Soft Drinks Industry Levy.
• The International Malnutrition Task Force: A Model for the Future?

Intergenerational Effects

• Meta-Analysis: Association of Gestational Hypertension and Preeclampsia with Offspring Adiposity.
• Maternal Supplementation of Probiotics, Prebiotics or Postbiotics to Prevent Offspring Metabolic Syndrome: The Gap between Preclinical Results and Clinical Translation.
• Maternal Programming by High-Energy Diets Primes Ghrelin Sensitivity in the Offspring of Rats Exposed to Chronic Immobilization Stress.
• Role of Excessive Weight Gain During Gestation in the Risk of ADHD in Offspring of Women with Gestational Diabetes.

Ecology, Evolution, & Energetics

• Predation Stress Experienced as Immature Mites Extends Their Lifespan.
• Is Torpor a Water Conservation Strategy? Heterothermic Responses to Acute Water and Food Deprivation are Repeatable Among Individuals of Phodopus sungorus.
• Trends in the Distribution of BMI, Waist Circumference and Prevalence of Obesity Among Taiwanese Adults, 1993–2016.

Methods

• A Comparative Study of Deep Learning Algorithms for Detecting Food Intake.
• Identifying Cancer Cachexia in Patients Without Weight Loss Information: Machine Learning Approaches to Address a Real-World Challenge.

Commentary

• Opinion: There Is No Evidence for a Far Transfer of Cognitive Training to Sport Performance.
• To Ease the World Food Crisis, Focus Resources on Women and Girls.
• Trimming the Fat from Obesity Science.
• Commentary: Intestinal Barrier Function and Immune Homeostasis are Missing Links in Obesity and Type 2 Diabetes Development.
• Facts, Narratives, Stigma, and Food Addiction.
• Changing the Subject on Obesity Prevention.
• The Goal Conflict Model: A Theory of the Hedonic Regulation of Eating Behavior.
• Comparison between Low Fat and Low Carb Diets.

General

• From the NIA: "We recently tracked trends from nine core study design elements identified as critical for rigor and reproducibility and evaluated them over five-year spans from 2000 to 2021. The results showed steady and significant improvement..."
• Ten Tips for Teaching Research Integrity to Early Career Students: A Perspective over 20 Years.
• Preprint: Factors Associated with Cancer Prevention/Risk Reduction Behaviors Among Latinos in Indiana.
• Preprint: “I Haven’t Been Diagnosed, but I Should Be”: Insight Into Self-Diagnoses of Common Mental Health Disorders.
• Preprint: How to Relate Potential Outcomes: Estimating Individual Treatment Effects Under a Given Specified Partial Correlation.
• September 2022 Update from Good Science Project.
• Adding Context to the Alzheimer’s Disease Research Fraud Charges.
• News: Cigarette Smoking More Prevalent, Harder to Quit Among Rural Vs. Urban Americans.

Announcements

• IU to Hire 100 New Tenure-Track Faculty at Bloomington Campus.
• JoAnn E. Manson is 2022 Recipient of the Alma Dea Morani Renaissance Woman Award, the Highest Honor Bestowed by the Women in Medicine Legacy Foundation.
• Search Announcement: Editors-In-Chief: Advances in Nutrition and Journal of Nutrition.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.

Featured

• Perspective: Key Causes and Contributors of Obesity.
• Relationship between Food Security Status in a Caregiver's Family of Origin and Current Feeding Practices Among Low-Income, Single, Female Primary Caregivers.
• Effects of Ambient Temperatures between 5 and 35 °C on Energy Balance, Body Mass and Body Composition in Mice.
• Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity.
• RCT: Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults with Obesity.

Headline vs Study

• Headline: Your Child's Weight Problems Could Be Caused by Inadequate Sleep.
• Press-Release: Insufficient Sleep in Teenagers Is Associated with Overweight and Obesity.
• Meeting Abstract: Sleep Duration and Its Association with (Not Necessarily Cause Of) Cardiometabolic Outcomes Among Adolescents Enrolled in the SI Program in Spain.

Contrary or Null Findings

• Meta-Analysis: "Tart cherry juice had no effect on total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), insulin, BMI, fat mass, systolic and diastolic blood pressure."
• Meta-Analysis: Probiotics in Bariatric Surgery Ensure Greater Lipids and Glycemic Profile with No Effect on Anthropometric Measurements and Inflammatory Markers.
• High Intakes of Iodine Among Women During Pregnancy and the Postpartum Period Has No Adverse Effect [association] on Thyroid Function.
• Meta-Analysis: "Coffee consumption has no effect on circulating markers of liver function but increases adiponectin concentrations."
• Meta-Analysis: "Sea buckthorn had no effect on blood sugar, blood pressure, and BMI of the overall subjects."
• No Statistically Significant Evidence for an Association between Ultraprocessed Food Intake and Overweight, Obesity, and Malnutrition Among Children in Tehran, Iran.
• RCT: "...in adults with pre-diabetes, this study examines the effect of six months of supplementation with probiotic and prebiotic interventions on the primary outcome of glycated haemoglobin (HbA1c) at six months...This study found no evidence of clinical benefit from the supplementation with either HN001 and/or OBG cereal on HbA1c or any secondary outcomes and does not support the clinical use of these interventions in populations with pre-diabetes."
• "Although lean NASH is considered to be more benign than obese NASH, our study suggests a paradoxical correlation of lean NASH with waitlist outcomes, and graft and patient survival post-LT."

Basic

• Contribution of the Co-Chaperone FKBP51 in the Ventromedial Hypothalamus to Metabolic Homeostasis in Male and Female Mice.
• MiR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism in Vitro and in Vivo.
• Rapamycin/metformin Co-Treatment Normalizes Insulin Sensitivity and Reduces Complications of Metabolic Syndrome in Type 2 Diabetic Mice.
• Alternate-Day Fasting Prevents Non-Alcoholic Fatty Liver Disease and Working Memory Impairment in Diet-Induced Obese Mice.
• Exon 2-Mediated Deletion of Trem2 Does Not Worsen Metabolic Function in Diet-Induced Obese Mice.

Scientific Rigor & Scholarly Dialogue

• Recommendations by the USDA Nutrition Evidence Systematic Review Team to Improve Research.
• Strengthening Research That Answers Nutrition Questions of Public Health Importance: Leveraging the Experience of the USDA Nutrition Evidence Systematic Review Team.

Clinical

• Thirty Obesity Myths, Misunderstandings, And/or Oversimplifications: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022.
• RCT: The Effects of Chitosan Supplementation on Anthropometric Indicators of Obesity, Lipid and Glycemic Profiles, and Appetite-Regulated Hormones in Adolescents with Overweight or Obesity.
• The Triglyceride Glucose-BMI: A Non-Invasive Index That Identifies Non-Alcoholic Fatty Liver Disease in the General Japanese Population.
• Facilitators and Barriers Influencing Weight Management Behaviours During Pregnancy.
• RCT: Effect of a Comprehensive Telehealth Intervention vs Telemonitoring and Care Coordination in Patients with Persistently Poor Type 2 Diabetes Control.

Children and Adolescents

• Review: Breakfast and School-Related Outcomes in Children and Adolescents in the US: A Literature Review and Its Implications for School Nutrition Policy.
• Lack of Evidence for a Causal Role of Hyperinsulinemia in the Progression of Obesity in Children and Adolescents.

Surgery

• RCT: A Smartphone Application to Improve Adherence to Vitamin and Mineral Supplementation After Bariatric Surgery.
• Investigating Relationships between Post-Prandial Gut Hormone Responses and Taste Liking Ratings Prior to and Following Bariatric Surgery.
• Comparative Safety and Effectiveness of Roux-En-Y Gastric Bypass and Sleeve Gastrectomy for Weight Loss and Type 2 Diabetes Across Race and Ethnicity in the PCORnet Bariatric Study Cohort.
• Roux-En-Y Gastric Bypass Alters Intestinal Glucose Transport in the Obese Zucker Rat.
• RCT: A Smartphone Application to Improve Adherence to Vitamin and Mineral Supplementation After Bariatric Surgery.

Drugs

• The Related Metabolic Diseases and Treatments of Obesity.
• Liraglutide and Exercise: A Possible Treatment for Obesity?
• Anti-Obesity Weight Loss Medications: Short-Term and Long-Term Use.
• Gastrointestinal Adverse Events of Semaglutide in Patients with Overweight or Obesity.

Food & Diet

• Scoping Review and Evidence Map on the Relationship between Exposure to Dietary Sweetness and Body Weight-Related Outcomes in Adults.
• Gut Microbiota and Host Genetics Modulate the Effect of Diverse Diet Patterns on Metabolic Health.
• RCT: Effects of Inulin Supplementation on Inflammatory Biomarkers and Clinical Symptoms of Women with Obesity and Depression on a Calorie-Restricted Diet.
• Review: The Effect of the Meat Factor in Animal-Source Foods on Micronutrient Absorption.

Caloric and Dietary Restriction

• 3-Bromopyruvate, a Caloric Restriction Mimetic, Exerts a Mitohormetic Effect to Provide Neuroprotection Through Activation of Autophagy in Rats During Aging.
• Systemic Lipolysis Promotes Physiological Fitness in Drosophila Melanogaster.

Exercise & Physical Activity

• Predicting Decisional Determinants of Physical Activity Among Older Adults: An Integrated Behavior Approach.
• Physical Activity and Sedentary Behavior in Children During the COVID-19 Pandemic: Implications for Mental Health.

Economics & Sociology

• Multiple Family Member Deaths and Cardiometabolic Health Among Black and White Older Adults.
• The “Jolly Fat” for the Middle-Aged and Older Adults in China, Was Education Level Considered?
• Gender Differentials in Prevalence and Distribution of BMI Categories Among Older Adults in Various Strata of Society in India.

Epidemiology

• The Neighbourhood Environment and Profiles of the Metabolic Syndrome.
• Sex Differences in the Association between Short Sleep Duration and Obesity Among US Adults.

Psychology & Neuroscience

• Silencing of Hypothalamic FGF11 Prevents Diet-Induced Obesity.
• RCT: Efficacy of a Food Response and Attention Training Treatment for Obesity.
• Changes in Hedonic Hunger and Food Reward After a Similar Weight Loss Induced by a Very Low-Energy Diet or Bariatric Surgery.
• RCT: Improved Food Go/No-Go Scores After Transcranial Direct Current Stimulation (tDCS) to Prefrontal Cortex.
• Functional Relationship between Inhibitory Control, Cognitive Flexibility, Psychomotor Speed and Obesity.
• Insufficient Sleep and Obesity: Cause or Consequence.
• Systematic Review: Association between Total Diet Replacement Programs and Mental Well-Being.

Equity and Disparities

• Analysis and Exploration on the Integration of Mental Health Education Into College Physical Education Practice.
• Potential Applications of Thyroid Hormone Derivatives in Obesity and Type 2 Diabetes: Focus on 3,5-Diiodothyronine (3,5-T2) in Psammomys obesus (Fat Sand Rat) Model.
• The Socio-Economic Inequality in BMI: A PERSIAN Cohort-Based Cross-Sectional Study on 20,000 Iranian Adults.

Stigma

• Examining How Framing Obesity as Disease Vs. Food Addiction Influences Stigma Among Fitness Practitioners.
• Adolescents with Overweight and School Health Nurses in Norway on Weight Stigma and Physical Activity.
• Systematic Review: Examining Weight Bias Before And/or After Bariatric Surgery.

Policy Related

• Integrating Framework Analysis, Scenario Design, and Decision Support System for Sustainable Healthy Food System Analysis.
• Systematic Review: Partnerships and Community Engagement Key to Policy, Systems, and Environmental Achievements for Healthy Eating and Active Living.
• Assessment of Calories Purchased After Calorie Labeling of Prepared Foods in a Large Supermarket Chain.

Intergenerational Effects

• Sex-Specific Effects of Maternal Weight Loss on Offspring Cardiometabolic Outcomes in the Obese Preeclamptic-Like Mouse Model, BPH/5.
• Prenatal Metabolomic Profiles Mediate the Effect of Maternal Obesity on Early Childhood Growth Trajectories and Obesity Risk.

Ecology, Evolution, & Energetics

• Reproduction, Postnatal Development and Resting Metabolic Rate of a Poorly Studied Subterranean Rodent, the Long-Clawed Vole (Prometheomys schaposchnikowi).
• Energy Consumption III—Performance Output.

Methods

• Perspective: A Rational Definition for Functional Foods.
• Use of Deep Neural Networks to Classify Images of Common Edible Nuts.
• Validation of Energy Expenditure and Macronutrient Oxidation Measured by Two New Whole-Room Indirect Calorimeters.
• Review: Outcomes Addressed in Lifestyle RCTs in Community-Dwelling Older People with (Sarcopenic) Obesity.
• Systematic Review: Examining Contributors to Misestimation of Food and Beverage Intake Based on Short-Term Self-Report Dietary Assessment Instruments Administered to Adults.

Commentary

• Everyday Foods and Cosmetics That Use Wild Plants May Be Harming the Environment.
• Gastrophysics: The Science of Dining by Charles Spence - and Commentary on Replicability of Some Behavioral Science.
• How About a Pumpkin Spice Tax to Fight Obesity?
• Hedonic Food Technology.
• Replacing Sugar: How, Now?
• Recommendations for RCTs on Bariatric Surgery.
• Endoplasmic Reticulum Stress in Metabolic Disorders: Opposite Roles of Phytochemicals and Food Contaminants.
• Experimental Studies on Androgen Administration in Animal Models: Current and Future Perspectives.
• Preventing Obesity—It Is Time for Multiple Policy Strategies.

General

• Psychological Inoculation Improves Resilience Against Misinformation on Social Media.
• Male Social Niche Conformance? Effects of Manipulated Opportunity for Extra-Pair Mating on Behavior and Hormones of Male Zebra Finches.
• Interplay of Plastic Pollution with Algae and Plants: Hidden Danger or a Blessing?
• Occam’s Razor Gets a New Edge: The Use of Symmetries in Model Selection.
• Immortal Jellyfish Genes Identified That May Explain Their Long Lives.
• The Proportion of RCTs That Inform Clinical Practice.
• Artificially Stimulating Retrotransposon Activity Increases Mortality and Accelerates a Subset of Aging Phenotypes in Drosophila.
• Researchers Challenge Claim of Historic Human Brain ‘shrinking’.

Announcements

• Call for Candidates: Editors-In-Chief for Advances in Nutrition and the Journal of Nutrition. Deadline for Applications: October 28, 2022.
• Indiana Partners with IU to Offer Telehealth Counseling in Rural Areas.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.

Featured

• Dogs Suppress a Pivotal Function in the Food Webs of Sandy Beaches.
• The White House Conference on Hunger, Nutrition and Health Is an Opportunity for Transformational Change.
• Improved Growth and High Inheritance of Melanocortin-4 Receptor (mc4r) Mutation in CRISPR/Cas-9 Gene-Edited Channel Catfish, Ictalurus punctatus.
• RCT: Comparative Dietary Effectiveness of a Modified Government-Recommended Diet with Avoidance of Ultra-Processed Foods on Weight and Metabolic Management in Children and Adolescents.

Headline vs Study

• Headline: “Astonishing” Effects of Grape Consumption and “Remarkable” Impacts on Health and Lifespans.
• Study: Grape Powder (Not Grapes) Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity... In Female Mice.
• Study: Behavioral and Genetic Changes of Grape Powder (Not Grapes)... In Female Mice.
• Study: Grape Powder (Not Grapes) Modifies Hepatic and Urinary Metabolite Profiles... In Female Mice.

Contrary or Null Findings

• No Significant Weight or BMI Changes in Adults with Obesity Initiating Medical Marijuana Treatment for Other Medical Conditions.
• Meta-Analysis: No Significant Effect of Prevention Efforts on BMI-Related Measures.
• "No significant pooled IIDs [interindividual differences in effects] were found for aerobic exercise nor resistance training demonstrating that there is currently a lack of convincing evidence to support the notion that true IIDs exist for the anxiolytic effects of exercise among adults with anxiety- and stress-related disorders."
• Risk of Postoperative Stiffness Following Multiligamentous Knee Injury Surgery Is Not Affected by Obesity: A Multicenter Study.
• "Contrary to expectations, we saw no differences in FFA or uric acid levels between control and mitotane birds, but RU486 temporarily decreased stress-induced uric acid levels."
• RCT: "Contrary to previous thinking, the use of elastic bands around the forefeet during squats can elicit increased myoelectric activity of hip muscles, with a magnitude often greater than when the band is placed around the thigh segments."
• RCT: "VO2max was unaffected by 6 months of daily Calanus oil supplementation in healthy, physically fit, normal to overweight men and women between 30 and 50 years old."
• RCT: "The often reported acute increase in BP after caffeine supplementation could not be confirmed in this cohort of normotensive young adults."
• Meta-Analysis of RCTs: No Significant Difference in Benefits of Low-Carbohydrate Diets Versus Low-Fat Diets on Metabolic Risk Factors in Adults with Overweight and Obesity at 24 Months.
• RCT: A Pragmatic Low Carbohydrate Diet Intervention Changes Neither Carbohydrate Consumption nor Glycemia in Adolescents and Young Adults with Type 1 Diabetes.

Basic

• Ceramide Metabolism Associated with Chronic Dietary Nutrient Surplus and Diminished Insulin Sensitivity in the Liver, Muscle, and Adipose Tissue of Cattle.
• Glucagon Receptor Signaling at White Adipose Tissue Does Not Regulate Lipolysis.
• Short-Term High-Fat Diet Consumption Increases Body Weight and Body Adiposity and Alters Brain Stem Taste Information Processing in Rats.
• Mitochondrial Fission in Hepatocytes as a Potential Therapeutic Target for Nonalcoholic Steatohepatitis.
• Of Mice and Men: Considerations on Adipose Tissue Physiology in Animal Models of Obesity and Human Studies.

Scientific Rigor & Scholarly Dialogue

• “Holden Thorp, the Editor in Chief of … [Science], Says It’s Time to Improve the Process of Correcting the Scientific Record.”.
• Exploratory Hypothesis Tests Can Be More Compelling Than Confirmatory Hypothesis Tests.
• Retraction: Single Joint Exercises Do Not Provide Benefits in Performance and Anthropometric Changes in Recreational Bodybuilders.
• High-Profile Obesity Research Funded by Singapore Cited for Fraud.
• Re-Analysis and Additional Information Needed to Inform Conclusions. Comment on Halenova et al. Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats. Molecules 2020, 25, 23.

Clinical

• Obesity Paradox in Coronary Thrombus Burden of Patients with Acute Coronary Syndrome.
• Signaling Pathways in Obesity: Mechanisms and Therapeutic Interventions.
• Associations of BMI, Fasting Insulin, and Inflammation with Mortality: A Prospective Cohort Study.

Children and Adolescents

• Hair Glucocorticoid Concentration, Self-Perceived Stress and Their Associations with Cardiometabolic Risk Markers in Swedish Adolescents.
• Metabolic and Morphological Profile in Skeletal Muscle of Healthy Boys and Girls.
• Meta-Analysis: Association between Sleep Duration and Early Pubertal Timing in Children and Adolescents.

Surgery

• Association between Neighborhood Food Environment and Bariatric Surgery Outcomes.
• Human Gut Microbiota After Bariatric Surgery Alters Intestinal Morphology and Glucose Absorption in Mice Independently of Obesity.
• Association of Insurance Coverage with Adoption of Sleeve Gastrectomy vs Gastric Bypass for Patients Undergoing Bariatric Surgery.
• Examination of Elective Bariatric Surgery Rates Before and After US Affordable Care Act Medicaid Expansion.

Drugs

• Influence of Obesity on Blood Pressure Responses to Antihypertensive Drug Therapy in an Urban Hypertension Specialty Clinic.
• Discovery of a Novel Anti-Obesity Meroterpenoid Agent Targeted Subcutaneous Adipose Tissue.
• Formulation and Evaluation of Orlistat Loaded Microsponges for the Treatment of Obesity.
• Systematic Review: Effect of Semaglutide and Liraglutide in Individuals with Obesity or Overweight Without Diabetes.

Food & Diet

• The Ecuadorian School Food Environment: Association with Healthy and Unhealthy Food and Beverage Consumption and BMI.
• High-Dimensionality Reduction Clustering of Complex Carbohydrates to Study Lung Cancer Metabolic Heterogeneity.
• Review: Scoping Review and Evidence Map on the Relationship between Exposure to Dietary Sweetness and Body Weight-Related Outcomes in Adults.
• Dietary Total Antioxidant Capacity in Relation to Metabolic Health Status in Adolescents with Overweight and Obesity.

Caloric and Dietary Restriction

• Network Meta-Analysis: Comparative Effectiveness of a Low-Calorie Diet Combined with Acupuncture, Cognitive Behavioral Therapy, Meal Replacements, or Exercise for Obesity over Different Intervention Periods.
• Cumulative Consumption of Sulfur Amino Acids and Risk of Diabetes: A Prospective Cohort Study.
• The Protective Effect of Intermittent Fasting and Physical Exercise on Obesity Through Changes in Muscle Diameter.

Exercise & Physical Activity

• Review: The Role of Exercise-Induced Myokines in Promoting Angiogenesis.
• Meta-analysis: Effects of Three Modes of Physical Activity on Physical Fitness and Hematological Parameters in Older People with Sarcopenic Obesity.
• Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults.

Economics & Sociology

• Spatial Analysis of Neighborhood Vitality Determinants on Physical Activity: A Case Study of Chicago.
• Preprint: What Does the MacArthur Scale of Subjective Social Status Measure? Separating Economic Circumstances and Social Status to Predict Health.
• RCT: Exploring the Effects of Added Sugar Labels on Food Purchasing Behaviour in Australian Parents.

Epidemiology

• Multi-Sectoral Data Linkages to Explore Associations between the Built Environment and BMI.
• How Do the Home Food Environment, Parenting Practices, Health Beliefs, and Screen Time Affect the Weight Status of European Children?: FEEL4DIABETES-STUDY.
• Exploring the Intersectionality of Family SES and Gender with Psychosocial, Behavioural and Environmental Correlates of Physical Activity in Dutch Adolescents: A Cross-Sectional Study.

Psychology & Neuroscience

• The Association between Sleeping Behavior, Obesity, Psychological Depression, and Eating Habits Among Adolescents in the Emirate of Abu Dhabi–United Arab Emirates.
• RCT: Effects of an Exercise Program on Brain Health Outcomes for Children with Overweight or Obesity.
• Exposure to a Hypercaloric Diet Produces Long Lasting Changes in Motivation.

Equity and Disparities

• Adherence to the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and Obesity-Related Cancer Risk and Mortality in Black and Latina Women's Health Initiative Participants.
• Variable Impacts on Reproductive Energetics May Render Oviparous Squamates More Vulnerable to Climate Warming Than Viviparous Species.
• Systematic Review: Dietary Transitions and Health Outcomes in Four Populations.

Stigma

• Changes in Weight Bias After Simulation in Pre-License Baccalaureate Nursing Students.
• Dissertation: Assessing Weight Bias Among Healthcare Professionals: Creation and Validation of an Instrument.
• Legal Evolution of a Law Against Weight Discrimination in the United States: A Focus on Massachusetts.

Policy Related

• Addressing American Obesity: A Policy Proposal.
• Review: Effectiveness of School-Based Nutrition Intervention Components on Fruit and Vegetable Intake and Nutrition Knowledge in Children Aged 4–12 Years Old.
• The Corporate Influence on Food Charity and Aid: The “Hunger Industrial Complex” and the Death of Welfare.
• 'What Do Doctors Think They Need to Know About Nutrition?’—a Qualitative Study of Doctors with Formal Nutrition Training.
• RCT: Perceptions of Two Energy Drink Health Warning Labels.

Intergenerational Effects

• Maternal and Fetal Factors Affecting Cord Plasma Leptin and Adiponectin Levels and Their Ratio in Preterm and Term Newborns: New Insight on Fetal Origins of Metabolic Dysfunction.
• Relationships between Intrauterine Fetal Growth Trajectories and Markers of Adiposity and Inflammation in Young Adults.
• Association between Fetal Abdominal Growth Trajectories, Maternal Metabolite Signatures Early in Pregnancy, and Childhood Growth and Adiposity: Prospective Observational Multinational INTERBIO-21st Fetal Study.
• Maternal Pre-Pregnancy BMI and Mental Health Problems in Early Adolescents from the 2004 Pelotas Birth Cohort.

Ecology, Evolution, & Energetics

• Individual Variation in Heat Substitution: Is Activity in the Cold Energetically Cheaper for Some Individuals Than Others?
• Metabolic Scaling Is the Product of Life-History Optimization.

Methods

• Correlation between Subcutaneous Adipose Tissue of the Head and BMI: Implications for Functional Neuroimaging.
• Cluster Randomised Trials with a Binary Outcome and a Small Number of Clusters: Comparison of Individual and Cluster Level Analysis Method.

Commentary

• When Is a Calorie Not a Calorie?
• Want to Lower Your Risk of Early Death? 3 Activities are Most Beneficial, Study Says.
• "No randomized controlled trials have been conducted on the guidelines put forth by those in the Fertility Diet book."
• A New Combination Therapy Hits the Mark.
• Physical Activity May Have a Stronger Role Than Genes in Longevity.
• Can You Be Healthy and Have Obesity? Not Really, Says Major Study.
• Can the White House Nutrition Conference Help?
• Moisture Meter Tackles Mycotoxins in Ghana's Grains.

General

• Substance Use Reaches 30-Year Low Among Indiana Youth, Survey Finds.
• Preprint: Bootstrap Inference in the Presence of Bias.
• A Metabolite Produced by Gut Microbes Represses Phage Infections in Vibrio cholerae.
• “In a Week, We Can Tell If Something Slows Aging”.
• Epigenetic ‘Clocks’ Predict Animals’ True Biological Age.
• Socioeconomic Impacts on Andean Adolescents’ Growth: Variation between Households, between Communities, and over Time.
• Beneficial Effects of Apigenin on the Transgenic Drosophila Model of Alzheimer's Disease.
• Hiding Chocolate Stashes or Amazon Purchases from a Partner? ‘Guilty’ Purchases May Have Benefits.

Announcements

• Indiana University Bloomington Recognized Nationally for Commitment to LGBTQ+ Students.
• IU Food Institute Open House.
• Nutrition 2022: Food for the Brain: Bridging the Nutrition and Neurology Scientific Communities.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.