Obesity and Energetics Offerings

Featured

• Scientists Solve Mystery Behind Contradictory Behaviours of New Weight-Loss Drugs.
• Physiological Markers in Females and Males After Multiple Bouts of Caloric Deprivation During Arduous Military Training.
• Pulmonary Cold Sensing Through Club Cells Triggers Adipose Thermogenesis to Ameliorate Obesity.
• Secretary Kennedy Launches the Real Food Show to Inspire Americans to Cook Healthy, Affordable Meals at Home.
• The Central Amygdala Gates Exogenous Glucagon-Like Peptide 1 Signals.

Headline vs Study

• Headline: Ketogenic Diets May Increase Cancer Risk in the Small Intestine.
• Headline: The Hidden Cancer Risk of Ketogenic Diets.
• Study: One Particular Diet that is Ketogenic (Not Necessarily All Diets That are Ketogenic) Mediates Intestinal Tumorigenesis Through Lipids Not Ketones... In Mice.

Contrary or Null Findings

• The Increase in Fat-Free Mass During Weight Loss Does Not Prevent Greater Than Predicted Reductions in Resting Energy Expenditure in Recreational Athletes.
• RCT: Confocal Laser Endomicroscopy with Duodenal Food Challenge Does Not Predict Triggering Food Items in Eosinophilic Esophagitis.
• Acute 1,3-Butanediol Co-Ingestion with Carbohydrate Does Not Improve Endurance Performance in Chronically Ketogenic Male Athletes.
• No Effect of Body Fat on Fat Oxidation Rates in Lean and Overweight Females When Aerobic Fitness Is Controlled and Muscle Mass Is Similar.
• "Contrary to dogma, both [Geniculate Ganglion] and [Trigeminal Ganglion] fibers innervate filiform papillae, extragemmal fungiform regions, and taste buds."
• "A. artaxerxes females, contrary to the preference-performance hypothesis, preferred ovipositing on G. sylvaticum, even though larvae feeding on G. sylvaticum were slightly smaller than those feeding on G. sanguineum."
• "Contrary to the vulnerability-stress hypothesis, self-esteem did not moderate the social media-body concern relationship."
• "Compared with placebo, GLP-1 receptor agonists showed no significant effect on smoking cessation..."

(Im)precision Medicine

• Alas, More Papers Conflating Outcome with Response: Obesity Phenotype Predicts Tirzepatide Super Responders.
• Alas, More Papers Conflating Outcome with Response: Cardiometabolic Effects of Semaglutide in Individuals with Type 2 Diabetes in the United Arab Emirates: Real-World 12-Month Outcomes and Predictors of Response.
• Alas, More Papers Conflating Outcome with Response: Decoding the Hallmarks of GLP-1RA Weight-Loss Super-Responders.
• Alas, More Papers Conflating Outcome with Response: Tirzepatide Efficacy and Tolerability According to Early Weight Response: A Post Hoc Analysis of the SURMOUNT-1 and SURMOUNT-2 Trials.

Scientific Rigor & Scholarly Dialogue

• Expert Reaction to Review Paper Looking at Protein Intake and Health and Lifespan in Humans, Rodents and Insects.
• Comment on “The Long-Term Cardiovascular Benefits of Metabolic and Bariatric Surgery Versus Pharmacological Therapies in Patients with Type 2 Diabetes and Obesity: A Systematic Review and Meta-Analysis”.

Basic

• Integrated Myocardial and Plasma Lipidome Across the Human Obesity-Heart Failure Spectrum.
• Maternal Obesity in Rats Results in Male-Specific Increases in Genome-Wide DNA Methylation in Postnatal Offspring Liver.
• Fat Depot-Specific Accumulation of Benzo(a)pyrene Metabolites in Rats Fed with Western Diet and Its Implications for Colon Cancer.
• A Cell-Free Browning Strategy: Exosomal MiR-21a-5p from ADSCs Targets PDCD4 to Reshape Adipose Metabolism.
• Transgenic Conversion of Omega-6 to Omega-3 Fatty Acids Via Fat-1 Reduces Obesity-Related Intervertebral Disc Degeneration.
• Pregnancy-Associated Immune Features in COVID-19 Link Fetal Protection to Heightened Maternal Viral Risk.

Clinical

• Cohort Study: Identification of an Obesity Subphenotype with Reduced Intestinal GLP-1 Expression and Heightened Response to Tirzepatide.
• Association of Diabetes Mellitus and Obesity with Early Complications After Surgical Tracheostomy in Critically Ill ICU Patients.
• Effect of Testosterone Addition to Nutrition and Exercise on Muscle Mass in Men with Cirrhosis: The Next Trial.

Children and Adolescents

• RCT: Family-Centered Child Obesity Treatment.
• Home and Neighborhood Food Environment Measures and Weight-For-Age Z-Scores Among Children Aged 1-5 Years: An Exploratory Cross-Sectional Analysis.
• Association of Weight Status and Quality of Life Through Childhood and Adolescence: Australian Longitudinal Cohort Analysis.
• Narrative Review: Current and Forthcoming Pharmacotherapies for Adolescent Obesity.
• Quality Improvement Initiative to Implement a Hybrid Intensive Health Behavior and Lifestyle Treatment Program in Pediatric Primary Care.
• Parent-Adolescent Communication About Physical Activity, Weight, and Emotional Responses in Adolescents with Overweight/Obesity and Asthma.

Surgery

• MicroRNAs and Bariatric/Metabolic Surgery: Biomarkers, Mediators of Metabolic Remission, or Both?
• Cross-Sectional Study: Association between Anthropometric Measures and Abdominal Wall Thickness in Patients with Obesity: A Cross-Sectional CT Study.
• Retrospective Study: Analysis of Risk Factors for Delayed Extubation After Surgical Anesthesia in Patients with Obesity Undergoing Abdominal Laparoscopic Surgery for Gastrointestinal Diseases.
• Prospective Cohort Study: Lipoprotein Quality and Increased Epicardial Fat Volume in Non-Diabetic Normolipidemic Individuals with Obesity Normalize After Bariatric Surgery.

Drugs

• Review: Pharmacologic and Non-Pharmacologic Interventions for Hypothalamic Obesity.
• Eating Disorder Risk and Screening in Patients Using GLP-1RAs: Lessons Learned from Metabolic and Bariatric Surgery.

Food & Diet

• Perspectives on the Protein Recommendations in the 2025-2030 Dietary Guidelines for Americans.
• Review: The Hallmarks of Protein and Amino Acid Restriction in Aging and Longevity.

Caloric and Dietary Restriction

• Calorie Restriction and Skin Aging.
• Protocol: Rationale and Design of Traditional and Adaptive Calorie Restriction and Time-Restricted Eating Interventions Used in the Dietary Approaches to Longevity and Health (DiAL Health) Pilot Trial.
• Lifespan-Extending Effects of Prunus mahaleb L. Extracts in a Yeast Model: Comparison with Extreme-Caloric Restriction.
• Is Obesity a Reversible Disorder of Hippocampal Neuroplasticity? A Hypothesis Linking Caloric Restriction to Restoration of Memory Function.

Exercise & Physical Activity

• Physiological Markers in Females and Males After Multiple Bouts of Caloric Deprivation During Arduous Military Training.
• RCT: Dietary Nitrate Supplementation Reduces Performance Decline During Repeated Sprint Exercise Independent of Sex.
• Meta-analysis: Effects of Caffeine Intake on Swimming Performance.

Economics & Sociology

• Understanding the Association between Neighborhood Type, Built Environment, and Overweight in China: Evidence from Hebei Province.
• Social Determinants of Hypertension and the Role of Obesity Among Adults in India.
• How Low Could Semaglutide Prices Fall? An Analysis of Production Cost and Implications for Global Access.

Epidemiology

• Cross-Sectional Study: Obesity-Related Patterns of Multimorbidity and Their Association with Health-Related Quality of Life in Iranian Adults.
• Cross-Sectional Study: Pathways Linking to Behavioural and Biological Risk Factors on Diabetes and Overweight/Obesity Among Adults in Urban Slums from Western India.
• Retrospective Study: Maternal BMI and Risk of Post-Partum Haemorrhage: A Population-Based Study in Primiparous Women.
• Cohort Study: What Is the Contribution of Maternal BMI to the Risk of Adverse Pregnancy Outcomes?
• Hyperandrogenism in Combination with Obesity Associated with Increased Risk of Hypertensive Disorders of Pregnancy After Frozen Embryo Transfer.

Psychology & Neuroscience

• Opinion: Body and Mind: How Obesity Triggers Neuropsychiatric and Neurodegenerative Disorders.
• Associations between Weight Status, Peer Victimization, and Mental Health in Clinically Referred Children.
• Postoperative Evolution of the Addictive Pattern in Patients with Obesity Undergoing Bariatric Surgery.
• Exploring the Relationship between Social Media Use, Eating Behaviors, and Depression in Young Women.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Water Intake Mediates Cross-Sectional Associations between Urinary Kidney Injury Biomarkers and Race in Emerging Adults.
• Prospective Study: Racial Disparity in Immune Response: Prospective Study in Obesity-Associated Lupus Patients.
• GLP-1 Receptor Agonists in Primary Care: Readiness, Equity, and the Risk of a Two-Tiered Obesity Treatment Landscape.
• Report: Health and Dietary Disparities in the North of England. (pdf)
• Systematic Review: Geographical Disparities and Temporal Trends of End Stage Kidney Disease Incidence.
• Cross-Sectional Study: Socioeconomic Inequalities in Women's Malnutrition Across 70 Low and Middle-Income Countries.

Stigma

• Rethinking Weight-Centric Models: Advancing Weight-Inclusive Care for Black Women.
• Weight Bias Internalization and Thinness-Oriented Body Dissatisfaction Explain the Link between Experienced Weight Stigma and Thinness-Oriented Disordered Eating.
• Review: School-Focused Interventions for Weight-Based Victimization in Youth.

Policy Related

• Evaluation of Planning Policy to Regulate Takeaway Food Outlets for Improved Health in England: Synopsis.
• Ten-Year Impact of a Summer Meals Collaborative Model: An Innovative Approach to Enhancing the Reach and Efficiency of the Summer Food Service Program.
• When School Meals are No Longer Free: A Qualitative Exploration of Elementary School Teachers’ Experiences and Perceptions.
• The WHO Acceleration Plan to Stop Obesity: A Joint WHO/UNICEF Operational Model for Designing and Implementing the Response.
• Systematic Review: One Diet, Many Indices: Heterogeneity in Measuring Adherence to the EAT-Lancet Planetary Health Diet.
• Stakeholder Perspectives on the Double Burden of Malnutrition in Bangladesh: Policy Architecture and Implementation Challenges.

Intergenerational Effects

• Maternal Exercise Is Associated with Enhanced Systolic Reserve and Altered Mitochondrial Respiration in Adult Female Offspring.
• Preprint: Maternal Obesity and Offspring Adiposity Trajectories During Early Childhood.
• Prospective Cohort Study: The Association of Maternal Obesity and Gestational Diabetes During Pregnancy with Offspring Adiposity and Dysmetabolism.
• Maternal Myo-Inositol Supplementation During Lactation in Rats Improves Offspring Metabolic and Cognitive Health and Mitigates Impairments Induced by Maternal and Adult Exposure to an Obesogenic Diet.
• Human Breast Milk as an Early-Life Functional Food: Metabolomic Perspectives on Growth and Stunting.

Ecology, Evolution, & Energetics

• Targeted Behavioural and Microclimate Data Collection Substantially Improves Biophysical Model Predictions of Energy Expenditure in Wild Birds.
• Dynamics of Resting Metabolic Rate and Innate Immune Response in Malaria-Infected Eurasian Siskins.
• Dissertation: Captivity and Its Implications for Western Lowland Gorilla (Gorilla gorilla gorilla) Nutrition, Physiology, and Cardiovascular Health.
• The Energetic Costs of Escaping Predation in Wild, Schooling White Mullet (Mugil curema).

Methods

• Podcast: Is Ultrasound Lying About Your Gains?
• Evaluating a Large Language Model for Identifying Key Comorbidities in Discharge Summaries of Patients with Obesity: A Comparative Validation Study Against ICD Codes Using MIMIC-IV.
• Microfluidic Chips in Obesity Research: A Review on Natural Products and Invertebrate Models for Obesity Management.
• CD36-Mediated Metabolic Changes in Tbet+CD11c+ B Cell During Obesity.

Mathematical and Quantitative

• Subgroup-Specific Cardiovascular Associations of Intensive Lifestyle Intervention: A Causal Forest Analysis in Adults with Type 2 Diabetes and Overweight/Obesity.

Commentary

• Time-Restricted Eating Preserves Cognitive Function in Adults.
• Podcast: Did Low-Fat Diets Drive the Obesity Epidemic? | Dr. Arne Astrup & Mike Haney.
• Podcast: Digging Into Food Insecurity with William Nall, Global Food Strategist.
• Protein Restriction Improves Metabolism and Longevity.
• Podcast: BrainStuff Classics: Is Canned Food Really Worse Than Fresh or Frozen?
• Podcast: "If you made everyone give you the raw information of epidemiology papers, I suspect 60%, 70% or 80% would be found to be false, fraudulent or worse, or maybe slightly better, but probably worse. There'll be something really problematic with this data."
• 'We Have No Freaking Clue' What Weight-Loss Drugs are Doing to Your Brain, Warns Cambridge Professor.
• Karl-Anthony Towns, Food Noise, and Why GLP-1 Drugs Quiet the Brain.

General

• New Approach Helps Scientists Uncover Disease-Linked Genes That Traditional Methods Can Miss.
• Rare Contagious Cancer Discovered in Wild Catfish.
• Podcast: Statins - Time to Stop the Worry!
• No Evidence of Experimenter Demand Effects in Three Online Psychology Experiments.
• Is It OK to Eat the Same Things Every Day?
• FDA Expert Panel Backs Compounding of Six Peptides.
• Is Interdisciplinary Science Worth It?
• A Closer Look at Brain Tissue Vulnerability in Neurological Disease.

Video & Audio

• Research on Weight Gain and Obesity.

Announcements

• NIH Selects Dr Courtney Aklin as Director of the National Institute of Nursing Research.
• CME Online: Sept 16-19 2026 - Mental Health and Metabolic Health: The Science and Art of Integrated Care.
• John Speakman, Aberdeen Academic Recognised by Polish Academy of Sciences for Outstanding Contribution to Science.
• Medical Research Council and British Heart Foundation Fund £72 Million Research Institute to Tackle UK Obesity.

Featured

• You are when you eat: How food synchronizes liver clocks.
• Podcast: Is It Really Just Calories In, Calories Out? Metabolism, Insulin, Hormones and Why Counting Fails.
• Editorial: Inconvenient for the Investigator but Convenient for Science: Trial Registration in the American Journal of Clinical Nutrition.
• Reframing Basic Experimental Studies in Humans - Implications for Nutrition Science.

Headline vs Study

• Social Meta Title: Scientists Studied What Fathers Eat Before Conception. It Showed Up in Their Babies.
• Study: Associations between fathers' self-reported intake and neonatal anthropometric outcomes. Whether it "showed up in their babies" was not measured. "It is important to emphasize the need for additional research to determine the causality of the associations observed..."

Contrary or Null Findings

• "Amenorrheic athletes did not demonstrate cardiovascular disease risk factors compared with eumenorrheic athletes, contrary to what has been observed in prior studies of adult athletes."
• "...contrary to our predictions, this high-quality dietary supplementation resulted in lower vaccine responsiveness."
• "Greater adiposity was associated with shorter QTcF, contrary to the conventional paradigm."
• "Contrary to the study hypothesis, this study suggests no differential effects of the intervention [dietary counseling] across educational groups."
• "Contrary to hypotheses, ADHD diagnosis did not moderate these associations, suggesting shared neural pathways linking early adiposity and brain structure independent of diagnostic status."
• RCT: Betaine Supplementation Has No Effect on Sex Hormones in Premenopausal Women with Overweight or Obesity.
• Meta-Analysis: Number of Sprint Repetitions in a Sprint Interval Training Session Does Not Moderate Improvements in V̇O₂max with Training.
• Unintentional Weight Loss Does Not Predict Poor Outcomes in Zenker Diverticulum.

Basic

• Sucralose Is Accumulated in Adipose Tissue and Plasma, but Minimally Impacts Inflammation in Lean and Obese Mice Available to Purchase.
• BMI Normalization Is Associated with Lower Risk of Progression to Type 1 Diabetes, Primarily in Youth.
• Oral Co-Delivery of Quercetin and Anthocyanins Via Dual-Ligand Nanoparticles Alleviate Obesity and Associated Metabolic Disorders.

Scientific Rigor & Scholarly Dialogue

• Podcast: Effectiveness of Chiropractic Spinal Manipulation for Headache Treatment.
• Discrepancies between Validated and Selected Dietary Exposures for Association Analysis: A Meta-Research Study of Cohorts Examining Diet-Cardiovascular Disease Associations.
• Expert Reaction to Unpublished Study Suggesting That Diet Quality Matters More Than Food Processing Level.

Clinical

• RCT: Influence of Protein Intake During Obesity Reduction on Physical Function and Body Habitus in Older Men with Prediabetes.
• Sugar Rationing During the First 1000 Days and Early-Onset Cancer: A Natural Experiment.
• Interpreting Lower HDL-C in Plant-Based Diets: Mechanisms and Clinical Implications.
• Declines in Plasma Erythritol Levels and Improvements in Insulin Sensitivity and Glucose Metabolism: POUNDS Lost Trial.
• Commentary: Are We Measuring the Same Disease? Clinical Obesity as a Definition-Dependent Construct.
• Real-World Data-Driven Insights in Obesity: A Comparative Cross-Sectional Analysis of General Practice and a Specialized Obesity Clinic in Belgium - An IMI2 SOPHIA Study.

Children and Adolescents

• Association of Early Childhood Lifestyle Patterns with Overweight in Preschoolers and Timing of Adiposity Rebound.
• Identifying Eating Behaviour Phenotype Cut-Off Scores for Childhood Obesity: An Individual Participant Data Meta-Analysis Using the Child Eating Behaviour Questionnaire (CEBQ).
• Infections in Infancy and Association with Long-Term Weight Gain and Obesity in Children, Southern California, USA.
• Review: Unravelling the Obesity Epidemic Among Young People in Qatar.
• Physical Activity Participation and Obesity-Related Risk Behaviors Among Male Saudi Adolescents.
• Association of Parental Moderate-To-Vigorous Physical Activity with Child Overweight/Obesity, Physical Fitness and MVPA Guideline Adherence: Dose-Response Analyses Among Schoolchildren.
• Associations between Physical Activity and Physical Fitness in Preschool Children: Gender and Age Differences.
• Increasing Trend in Prediabetes and Obesity Among Adolescent School Children in Chennai City in Southern India.

Surgery

• Associations between Obesity-Related Comorbidities and Weight Loss After Bariatric Surgery.
• Meta-analysis: An Updated Systematic Review, Meta-Analysis, and Network Meta-Analysis of Breast Cancer Incidence After Metabolic and Bariatric Surgery.
• Commentary: Beyond Blood Pressure Reduction- the Potential Cardiovascular Risk Reduction Benefits of Weight Loss Surgery.
• Bariatric Surgery in Adolescents with Obesity: Weight and Cardiometabolic Outcomes-Real-World Data.

Drugs

• Orforglipron: First Approval.
• Glucagon-Like Peptide-1 Receptor Agonists and Risk for Anterior Ischemic Optic Neuropathy.

Food & Diet

• RCT: Grazing Suppresses Meal-Induced Dietary Preference in Rodents and Humans.
• Toddler Diet Quality: A Factor Associated with Childhood Growth?

Caloric and Dietary Restriction

• Caloric Restriction Enhances Radiosensitivity of Colorectal Tumors Through the CGAS-STING Pathway Activation.
• High-Fat Diet Triggers Chemerin-Dependent Immune Reprogramming That Exacerbates Acute Kidney Injury.

Exercise & Physical Activity

• Leisure-Time Physical Activity on Age-Modelled Trajectories of BMI and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Electronic Health Record Data from the CORDELIA-Catalunya Study.
• Body Appreciation and Social Anxiety: Exploring Within-Person Associations and the Moderating Role of Physical Activity.
• Physical Activity Relates to Adolescent Social Anxiety: Evidence from a Structural Equation Model Involving Resilience and Self-Efficacy.
• Systematic Review: Association between Sensor-Based Physical Activity, Sedentary Behaviour, Sleep, and Mental Health in University Students.
• Meta-Analysis: Comparative Effectiveness of School-Based Physical Activity Interventions on Moderate-To-Vigorous Physical Activity in Children and Adolescents.
• Mediation Analysis of Fundamental Movement Skills, Physical Activity, Fitness, and BMI in Primary School Children.
• Exploring the Associations Among Physical Activity, Social Adaptation, and Emotional Intelligence in Adolescents: A Network Analysis Study.

Economics & Sociology

• Dissertation: Investigating the Interrelationships of Alcohol Consumption, Physical Activity, Socioeconomic Status, and Obesity: A Multi-Method Approach.
• Socioeconomic Inequalities in Obesity Among Korean Adults: The Role of Lifestyle Factors in KNHANES 2022–2024.
• Systematic Review: Socioeconomic Position and the Hair Cortisol-Obesity Association.
• The Economic and Social Burden of Obesity in Bulgaria.
• GLP-1-Induced Weight Loss and the Female Obesity Penalty.

Epidemiology

• Clinical Value of the New Obesity Definition for Cardiovascular Events in a Middle Eastern Population.
• Prediabetes Phenotypes and Adiposity Patterns: Findings from a Population-Based Study.
• The Degree of Obesity Correlates with the Severity of Acute Pancreatitis.
• Global Burden of Gout Attributable to High BMI (1990-2021) and Causal Link with Obesity: A GBD and Mendelian Randomization Study.

Psychology & Neuroscience

• Psychophysiological Pathways Linking Physical Activity and Mental Health in Adolescents: A Narrative Review of Autonomic Regulation, Hypothalamic-Pituitary-Adrenal Axis Function, Neuroplasticity, and Sleep Rhythms.
• Letter: Distinct Brain Regions Mediate Regulation of Food Intake in Response to GIPR Agonism or Antagonism.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Local Community Environment Drive India’s Obesity Epidemic: A Multilevel Analysis of Geographic Variations Using Asian-Specific BMI Criteria.
• Engaging Stakeholders to Define Research Priorities and Build a Research Community to Reduce Obesity Among Hispanic Women in the Southeastern United States.
• Sleep Duration and BMI Among Adolescents: Variation by Age and Race/Ethnicity.
• Existing Geographical Disparities in the Utilization of Counseling Services by Pediatric Patients with Obesity.
• Global, Regional, and National Trends in the Morbidity Gap and Contributing Diseases, Injuries, and Risk Factors, 1990-2023: A Systematic Analysis for the Global Burden of Disease Study 2023.

Stigma

• Attitudes, Stigma and Knowledge on Obesity in Mexico: A National Cross-Sectional Survey of the General Population and Healthcare Professionals Living with or Without Obesity.
• Review: Weight Stigma in Latin America and the Caribbean: Regional Evidence and a Call to Action by ABESO.

Policy Related

• Support for an Added-Sugar Menu Labeling Policy Among Key U.S. Population Groups in a Cross-Sectional Sample.
• Perspective: Informing the Next Chapter of SNAP Policy: Lessons from SNAP Participants’ Experiences in the Aftermath of the Emergency Allotment Expiration.
• Systematic Review: Implementation Strategies Used in Effective Policies to Combat Obesity in Socioeconomically Disadvantaged Communities.
• State Supplemental Nutrition Assistance Program Policies and Cardiovascular Mortality.
• Mexico’s Soda Tax as a Public Health Lever: A Case Study on Tackling Obesity and Diabetes Through Fiscal Policy.
• Changes in Physical Fitness in Chinese Primary Schools Following the “Double Reduction” Policy Based on Policy Instrument Theory.

Intergenerational Effects

• Effect Modification by Ambient Temperature on the Association of Ambient Ozone Exposure with Diet-Controlled and Insulin-Treated Gestational Diabetes Mellitus.
• Temporal Trends and Determinants of Gestational Diabetes Mellitus and Perinatal Outcomes in Tuscany, Italy (2010-2021).
• Weight-Gain-For-Gestational-Age Z-Score in Twin Pregnancies in China and Its Association with Preterm Birth: A Retrospective Cohort Study.
• Maternal Vitamin B12 Deprivation Exacerbates Offspring Obesity by Reducing Early-Life Colonization with Bifidobacterium pseudolongum.
• Hypertensive Disorders of Pregnancy: Heterogeneity in Risk Factors and Maternal and Neonatal Outcomes Across Subtypes - A 6-Year Retrospective Cohort Study.

Ecology, Evolution, & Energetics

• Diet-Microbiome Synergy Underlies Obesity-Associated Immunotherapy Efficacy.

Methods

• Systematic Review: Applications of Artificial Intelligence in Cardiovascular Risk Detection and Prediction Among Adults with Obesity.
• News: New AI Body Map Reveals Obesity’s Hidden Attack on Facial Nerves.
• Generative AI-Enhanced Ensemble Model for Predicting Adolescent Obesity in India: A School-Based Study in Two Southern Districts of Karnataka.
• Same Child, Different Risk: Demographic Bias in Childhood Obesity Attribution by Large Language Models.

Mathematical and Quantitative

• A Social Influence-Driven Compartmental Model of Obesity Dynamics with Multi-Class Severity and Relapse.

Commentary

• Podcast: Catching Up with Dr. Mary Newport | Ketosis, Cholesterol and Brain Health.
• Podcast: GLP-1 Therapy and Bone Density: Separating Signal from Noise with Dr. Sandra Cortina.
• Podcast: Are Your Peptides Illegal?
• Let's Not Throw the Baby Out with the Bath Water-Next Steps for Child Obesity Prevention in Early Life.
• Transforming Screen Time Into Active Time: Digital Health Interventions for Childhood Obesity.
• Review: Diagnosis, Staging and Management of Obesity: A Synthesis of Contemporary Guidelines.
• Ketogenic Diet, in a First Randomized Trial, Correlates with Symptom Improvement in Schizophrenia & Bipolar Disorder with Psychosis.
• Obesity Ad Wars: Only in America.

General

• Podcast: Are You Still Assuming Every Newborn Got Vitamin K?
• Podcast: Are We Too Afraid of the Sun?
• The Best of Both Worlds - Using Clinical Trial and Observational Data to Evaluate Vaccine Protection.
• Geroprotective Insights Into the Natural Metabolite Spermidine in Aging and Age-Related Diseases. (pdf)
• "Contrary to our hypothesis, testosterone declined more in fathers who reported higher alignment with traditionally masculine beliefs, and among those who did not identify as the child's primary caregiver."
• Caffeine and Cardiovascular Disease: A Scientific Statement from the American Heart Association.
• Orcas Seen Ramming Prey So Hard It Explodes May Be Playing Game.
• An Automated Approach to Improve Clinical Trial Registration and to Identify Outcome Changes on ClinicalTrials.gov.
• "...62% of U.S. adults self-report having little to no idea what statistics or statistical concepts like p-values are, but 90% of them would base decisions on reported statistics at least sometimes if they understood them better."

Announcements

• Childhood Obesity Advancing Editorial Processes.

Featured

• A Cold-Induced GDF15-Secreting Adipocyte Subpopulation Regulates Energy Homeostasis Through Endocrine Signaling.
• RCT: "Incorporating 1 avocado per day into habitual diets for 26 weeks reduced the concentration of atherogenic LDL particles without affecting other lipoprotein particles and subclasses in adults with abdominal obesity."
• Podcast: Is Your Protein Aging You? What the Longevity Science Gets Wrong.
• Video: Gary Taubes - NIH Scientific Freedom Lecture Series: Energy Balance or Fuel Partitioning? A History Lesson in the Science of Obesity Pathogenesis, and Its Implications.

Headline vs Study

• Headline: Fish over Meat: Why a Pescatarian Diet May Help People with Obesity Live Longer.
• Study: Associations between mortality and being categorized as a meat eater, fish eater, or vegetarian/vegan based on self-reported dietary intake. Causation not established. "[P]escatarian diet was associated with better survival outcomes [compared to meat eaters], whereas vegetarian and vegan diets did not," which would be "Fish over Non-Fish."

Contrary or Null Findings

• RCT: "The ME [mindfulness-based eating] group showed no clear improvement in inhibitory control on the food Go/No-Go task," the primary endpoint.
• Systematic Review: "Nutrition education may be effective for intermediate outcomes such as nutrition knowledge and dietary behaviors, but evidence for effectiveness in physiological and biochemical outcomes remains inconclusive."
• RCT: "No significant group-by-time interactions were identified in the intention-to-treat analyses" in "Effects and moderators of a 16-week intervention on contextual physical activity in adults with moderate to severe depressive symptoms."
• Meta-Analysis: "There was no evidence of increased respiratory harm associated with weight-loss drugs compared with placebo, suggesting a reassuring respiratory safety profile in the general population."
• RCT: "Prolonged self-paced cycling in the heat produced a reproducible neuromuscular response dominated by slowed twitch relaxation. However, 6% CHO ingestion did not clearly attenuate these changes compared with PLA, suggesting that the principal impairment reflected exercise and heat load rather than CHO availability or delivery mode."
• RCT: "In elderly patients with chronic HF and malnutrition or at risk of malnutrition, a pragmatic nutritional intervention did not reduce major clinical outcomes."
• RCT: "In this randomized clinical trial of adults undergoing radical cystectomy, perioperative specialized immunonutrition did not reduce 30-day complications compared with standard oral nutrition. Differences in 2-year survival favored immunonutrition but were not statistically significant."
• RCT: In adults with RA and obesity, diet-induced weight loss reduced adiposity without evidence of disproportionate muscle loss.

Basic

• Combined Time-Restricted Feeding and Physical Exercise Attenuate ER Stress and Improve Liver Inflammation and Collagen Deposition in Aged Mice.
• Sleeve Gastrectomy Induces Adipose Browning Via Suppression of Asprosin and Activation of the ATF3-Nrf2/HO-1 Axis.
• ASK1-Induced FGF21 Synthesis in the Liver Prevents Obesity in Mice.
• Reduced Platelet Count in Mice Protects Against Glucose Intolerance and Beta Cell Loss During a Long-Term High-Fat Diet.

Scientific Rigor & Scholarly Dialogue

• PubPeer Comments On: Social Stress Shortens Lifespan in Mice.
• Editorial: WHO's Misguided Push for Complementary and Alternative Medicine.

Clinical

• Review: From Obesity to Healthy Longevity: A Consensus-Based Clinical Framework for Obesity Diagnosis, Staging, and Treatment.
• Systematic Review: Dietary Strategies and Nutritional Management in Patients Receiving GLP-1 and Dual GIP/GLP-1 Receptor Agonists as Adjuncts to Lifestyle Interventions.
• Perspective: Rethinking Cardiometabolic Therapy Thresholds in Individuals with Obesity.
• Central Obesity and Recurrent Cardiovascular Events in Patients with Obstructive Sleep Apnea.
• RCT: Longitudinal Association of Dietary Spermidine with Hepatic Function Indexes and Cardiometabolic Traits in Older Adults with Metabolic Syndrome.

Children and Adolescents

• Research Letter: GLP-1 Receptor Agonist and Bariatric Surgery Utilization Among Adolescents and Young Adults.
• Branched Chain Amino Acid Metabolism and Microbiome in Adolescents with Obesity During Weight Loss Therapy.
• Nutritional and Behavioral Determinants of Overweight and Obesity Among School-Aged Children in Shandong Province, China.

Surgery

• Perceptions and Attitudes Towards Obesity and Metabolic and Bariatric Surgery for Weight Loss in Children and Adolescents: A Survey Among a Subset of Chinese Residents.
• Optimal Timing of GLP-1 Receptor Agonist Initiation in Patients with Obesity Eligible for Metabolic Bariatric Surgery.
• Pilot Study: Bariatric Surgery and Patient Reported Outcomes of Heart Failure in Women.
• A Modified POSE 2.0 Double Helix Megaplication Endoscopic Gastroplasty Pattern for Obesity: Initial One-Year Outcomes in Japan.
• Evolving Utilization of Bariatric Surgery Since the Rise of Semaglutide and Tirzepatide.
• Intraoperative Liver Biopsy During Metabolic and Bariatric Surgery: Diagnostic Yield, Safety, and National Trends.
• Postoperative Changes in Eating Behavior After Sleeve Gastrectomy are Associated with IL-10 Independent of Anthropometric Changes.

Drugs

• RCT: Short- and Long-Term Effects of Semaglutide 2.4 mg on Energy Intake, Appetite, and Food Reward.
• RCT: Once-Weekly Semaglutide in Adults with Alcohol Use Disorder.
• Post-Shortage Compounded GLP-1 RA Market in 2 States with Potentially High Demand.

Food & Diet

• RCT: Lipoprotein(a) Lipidome and Diet: Responses to Reducing Saturated Fat Intake in African Americans.
• RCT: Replacing Red Meat with Non-Soy Legumes Alters Choline Metabolites but Not Systemic Inflammation or Proxies of Gut Barrier Function in Healthy Males.
• RCT: Comparison of Two Nutritional Protocols in Body Re-Composition of Resistance-Trained Participants.

Caloric and Dietary Restriction

• Defining a Ketone Threshold for Weight Loss: Evidence from 14 Day Daily β-Hydroxybutyrate Monitoring in 217 Subjects on a Ketogenic Diet.
• RCT: Time-Restricted Eating During a Bulking Phase Is Associated with Reduced Fat Accumulation, While Muscle and Strength Gains are Maintained.

Exercise & Physical Activity

• Changes in Self-Esteem, Body Dissatisfaction, and Body Appreciation During Face-To-Face and Digital Supervised Physical Activity Interventions in Women with Obesity.
• Associations of Demographic, Socioeconomic, Lifestyle Factors and Comorbidity with Accelerometer-Measured Physical Activity in Adults with Cardiovascular Diseases.
• Meta-Analysis: Muscle-Strengthening Activities are Associated with Lower Risk and Mortality in Major Non-Communicable Diseases.
• Long-Term Resistance Training with All-Cause and Cause-Specific Mortality: Assessing Dose-Response and Joint Associations with Aerobic Physical Activity.
• Dose-Dependent Association between Muscle-Strengthening Activities and All-Cause Mortality.

Economics & Sociology

• Associations of Educational Attainment with Cardiometabolic Markers and Health Behaviors.
• Changing Dynamics of the Education-Overweight Relationship in Indonesia: An Instrumental Variables Analysis.
• Obesity Related Out-Of-Pocket Expenditure and Productivity Loss: Evidence from Cross-Sectional Study in Bangladesh.

Epidemiology

• Preprint: Effectiveness of Telehealth Low-Carbohydrate Intervention in Preventing Chronic Kidney Disease.
• Meta-Analysis: Impact of BMI on All-Cause Mortality in Adults.
• Association between Metabolic Obesity Phenotypes and Alcohol-Associated Fatty Liver Disease Among US Adults.

Psychology & Neuroscience

• Screening, Diagnosis, Evaluation, and Staging of Obesity in Adults: Standards of Care in Overweight and Obesity-2026.
• Pooled Analysis: Prolonged Short Sleep and Its Effect on Body Weight and Composition.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• The Impact of Physical Activity on Health Inequality Among Older Adults: Evidence from China.
• Systematic Review: Cost-Effective Somewhere, Decision-Relevant Everywhere? A Global Systematic Review of Economic Evidence for Newer Type 2 Diabetes Therapies.
• The Burden of Cardiovascular-Kidney-Metabolic Syndrome in High Versus Upper-Middle-Income Countries: Integrated Analysis of Trends, Inequality, and Risk Factors.
• When Skin Color/Race and Education Matter: Disparities in Obesity Among Brazilians (2013-2019).

Stigma

• Binge-Spectrum Eating Disorders and Higher BMI are Associated with Greater Negative Attitudes Towards Obesity.
• Maternal Weight Discrimination Experiences and Restrictive Feeding Practices are Associated with Child Body Dissatisfaction and Drive for Thinness.

Policy Related

• Perspective: Relevance and Implications of Precision Nutrition to Nutrition Education and Behavior Research, Practice, and Policy.
• Ten High-Priority Areas for Health Policy Research in 2026-2027.

Intergenerational Effects

• Metabolites Co-Correlating with Maternal Obesity and Gestational Weight Gain and Offspring Childhood Obesity.
• Review: Maternal Obesity During Lactation as a Hypertensive Cardiovascular Risk Factor in the Offspring.
• Association of Maternal Overweight/Obesity Metabolic Phenotypes with Longitudinal Foetal Anthropometric Measurements.
• Evaluation of Family History Burden in Obesity Among 6-7-Year-Old Children at Pre-School Screening in Southern Russian Cities.

Ecology, Evolution, & Energetics

• Coping with Lactation by an Ephemeral Forager as Pups Get Bigger: Energy Expenditure, Water Flux, Diet and Foraging Activity of Lactating Fish-Eating Myotis (Myotis vivesi).
• Acceptability and Impact on Health-Related Markers of a Sustainable Dietary Pattern.

Methods

• Exposure to Processing from Ultraprocessed Diets and in Feeding Studies.
• Transforming Obesity Medicine with Artificial Intelligence: Personalization, Precision and the Path Ahead.
• Classification and Severity Assessment of Obesity in Clinical Risk Prediction of Multimorbidity Trajectories.

Commentary

• Bad Idea #40 "The food system is fundamentally broken" with Jan Dutkiewicz.
• Podcast: How Does the Gut-Brain Connection Work?
• US Obesity Crisis: Not Losing Weight Despite Exercising? American Heart Association Study Reveals the Surprising Truth About Your Health Beyond the Scale, Blood Pressure and Cholesterol.
• Non-Pharmacological Interventional Strategies for the Management of Obesity in Aging.
• Role of Calorie Restriction Mimetics in the Management of Obesity in Aging.
• Lost Sleep Affects Weight, and Obesity Is Multifactorial.
• Metabolic Memory in the Gut: The Microbiota-Epigenetic Crosstalk Orchestrating Obesity Onset and Novel Therapeutic Landscapes.
• Building Health from Childhood: One Health Strategies for Obesity Prevention and Nutritional Education in Italy.

General

• Podcast: The Surprising Lack of Breakthroughs in Life Extension Science over 40 Years | Siim Land.
• Targeting Cellular Senescence in Dermatology: Senolytic and Senomorphic Strategies.
• Characterization and Potential Functions of Milk Fat Globule Membrane and Exosome Proteins in Donkey and Bovine Milk: A Comparative Data-Independent Acquisition Proteomic Analysis.
• Podcast: SSRI-Ously? Separating Fact from Fiction on SSRIs.
• Historic Drought in Northern Kenya Shifts Diet and Mobility Away from Traditional Pastoralism as Resource Security and Nutrition Falter.
• Multiomic Profiling of Responses to Clinical and Novel Bisphosphonates Reveals Extraskeletal Effects on Ageing Related Signatures.
• Podcast: Why Do Some People Eat Dirt?
• Researchers Uncovered a Novel Pathway That Causes Epilepsy.

Announcements

• Webinar: August 6th, 2026, 7:00-8:00pm Via Zoom Title: "I Think You Might Have Lipedema": Recognizing & Acting on Lipedema in Everyday Obesity Medicine Practice.

Featured

• Rod Bain and Agriculture Under Secretary for Research, Education, and Economics Scott Hutchins Discuss USDA Research Priorities.
• Cognitive Demands of Bipedal Locomotion During Human Foraging.
• "…limiting a single nutrient, the amino acid methionine, in the diet destabilized DNA organization and led to cancer cell death and increased animal survival."
• Treating Acquired Hypothalamic Obesity.
• The Impact of BMI on All-Cause Mortality Worldwide: A Mathematical Demonstration of Clinical Bias Regarding Causal Risk from Body Composition Measures.

Headline vs Study

• Headline: Yeast Food Supplement Helps Immune Cells Fight Cancer More Effectively.
• Study: Yeast β-Glucan Supplementation Supports Immunometabolic Anti-Tumor Responses and Reverses Obesity-Induced Dysfunction Via Trained Hematopoiesis... In Mice.

Contrary or Null Findings

• Meta-Analysis: "Current evidence indicates that fasting and CR exert minimal to no statistically significant impact on reproductive hormones in adults."
• RCT: "Maternal high-protein/low-glycemic-index diet during pregnancy impairs offspring lipid profile."
• RCT: "This kindergarten-family intervention showed directionally favorable but statistically uncertain effects on BMIz gain after small-sample correction..."
• RCT: No Compelling Evidence of Deleterious Effect of Three Daily Servings of Full-Fat Dairy for 12 Weeks on Body Weight, Body Composition, Energy Metabolism, Blood Lipids, and Dietary Intake of Adults with Overweight and Obesity.
• RCT: Recess Did Not Affect Physical Activity.
• RCT: "...no evidence to support that the administration of fluralaner to domestic dogs diverts the feeding profile of T. infestans to humans at 10 months post-intervention."
• RCT: "No significant group by time interaction was found for depressive symptoms" in “Resistance exercise training compared to a low-intensity sham for depressive symptoms in young women with analogue generalized anxiety disorder.”
• Meta-Analysis of RCTs: "Magnesium supplementation does not appear to improve insulin resistance in individuals with diabetes or prediabetes significantly."

Basic

• Skin Acetone as a Clinical Diagnostic Biomarker of Ketosis.
• Stress-Coping Phenotypes Shape Adipose Tissue Function and Plasticity and Modulate Metabolic Resilience.
• Myeloid MMP14 Couples Extracellular Proteolysis to Inflammatory and Metabolic Remodeling During Obesity.
• Adipose Tissue Overexpression of Nicotinamide Phosphoribosyltransferase Prevents Metabolic Dysfunction in Obese Mice Via Extracellular Vesicles.

Scientific Rigor & Scholarly Dialogue

• Preprint: A Systematic Review to Critically Appraise Methodological Rigour in Research on Ultra-Processed Food and Cardiovascular Disease and Hypertension.
• Judge Dismisses Splenda Lawsuit, Says Courts Wrong Place for Research Debate.
• Clark Atlanta University Walks Back Study on Waffle House Workers.

Clinical

• Ecnoglutide: First Approvals.
• Impact of Surgery-To-Conception Interval on Maternal and Perinatal Outcomes Following Laparoscopic Sleeve Gastrectomy: A Retrospective Cohort Study.
• The Role of Endocrine Factors in Childhood Obesity.
• New Open Access Book: Body Mass Index in Clinical Practice Edited by Samy I. McFarlane.

Children and Adolescents

• A Longitudinal Cohort Study of the Costs of Adolescent Obesity Into Young Adulthood.
• Effects of Positive Childhood Experiences in Adolescence on Obesity in Women.
• Longitudinal Examination of the Family Food Environment and Weight Status Among Children.
• Systematic Review: Risk Factors in the First 1000 Days of Life Associated with Childhood Obesity.

Surgery

• Meta-Analysis: Improvement of Obesity-Related Comorbidities After Bariatric Procedures.
• Review: Obesity and Cardiovascular Disease: Mechanistic Insights and Multimodal Management Strategies.
• What Bariatric Surgery Can Teach Us About Glucagon-Like Peptide-1 Agonist Weight Loss Therapy: Improving Long-Term Outcomes and Patient Care.
• Review: Advanced Robotic Liver Surgery.
• Analysis of the Outcomes and Postoperative Complications of Patients Undergoing Body Contouring Plastic Surgery After Weight Loss.

Drugs

• Kailera’s Oral GLP-1 Asset Sees 11% Weight Loss, Hits Goals in Chinese Phase 3 Obesity and Diabetes Trials.
• Setmelanotide for the Treatment of Acquired Hypothalamic Obesity.
• A New GLP-1 Pill for Diabetes, Semaglutide with Amylin, Data from China, and More from ADA 2026.
• Single Dose Creatine Improves Cognitive Performance and Induces Changes in Cerebral High Energy Phosphates During Sleep Deprivation.
• Review: The Impact of Glucagon-Like Peptide-1 Receptor Agonists on Objective Physical Activity in Adults.

Food & Diet

• Five-Year Patient-Reported Outcomes of Individualized Nutrition Therapy Supporting Nutritional Ketosis in Adults with Type 2 Diabetes.
• Validation of a New Self-Administered Dietary Salt Intake Questionnaire in Patients with Chronic Kidney Disease.
• Ultraprocessed Food Versus Diet Quality in Relation to Cardiometabolic Health and All-Cause Mortality: NHANES 1999-2018.
• Heyehui Attenuates Diet-Induced Obesity Via Regulating LEP/AMPK/ACC Axis and Restoring Intestinal Function in Mice.

Caloric and Dietary Restriction

• RCT: Caloric Restriction Improves Glycemic Control Via the Adiponectin-Ceramide Axis in Men and Women without Obesity.
• Methionine Restriction Plus Vitamin B12 Antagonism Overcomes Methionine Independence for Cancer Therapy.
• RCT: Marked Changes in One-Carbon Metabolism on a Low-Carbohydrate High-Fat Diet.
• Meta-Analysis: The Effects of Fasting and Caloric Restriction on Reproductive Hormones.

Exercise & Physical Activity

• Adverse Pregnancy Outcomes and Sedentary Behavior, Light-Intensity Physical Activity, and Daily Steps.
• In Obesity Treatment, Physical Activity’s Benefits Go Beyond Weight Loss, Says AHA.
• Physical Activity and Quality of Life in Children: Findings from the Health Oriented Pedagogical Project (HOPP).
• Meta-Analysis: Impact of High-Intensity Interval Training on Cardiometabolic Risk Factors in Youth with Overweight/Obesity.

Economics & Sociology

• The Association of Socioeconomic Status and Response to Pediatric Health Behavior and Lifestyle Obesity Treatment in Germany and Sweden.
• Obesity as a Potential Explanatory Factor in the Association between Socioeconomic Position and Multidimensional Cardiometabolic Risk.
• Inhibitory Control Mediates the Association between Perinatal PM2.5 Exposure and Childhood Obesity in Children in the PROGRESS Cohort, Mexico City.
• Exploring the Development and Prevention of the Childhood Obesity Epidemic in Barbados Using the Socio-Ecological Framework: A Qualitative Study.

Epidemiology

• NLRP3 Inflammasome Partially Mediates Genotoxic E. Coli Infection in Lean but Not in Genetically Obese Mice.
• Compositional Analyses of Accelerometer-Measured 24-H Movement Behaviors Among Adults with Normoglycemia, Pre-Diabetes Phenotypes, and Diabetes: A Population-Based Study.
• The Joint Association of Health-Enhancing Walking and Healthful Diet with Central Obesity: A Longitudinal Repeated-Measures Study.
• Metabolically Healthy Obesity Is Independently Associated with 20-Year Incidence of Cardiovascular Disease: Findings from the ATTICA Cohort Study (2002-2022).

Psychology & Neuroscience

• Food Neophobia Is Associated with Lower Self-Reported Physical and Mental Health.
• Diet Quality, Nutrient Adequacy, and Symptom Associations in ADHD: A Case-Control Study of Australian Adolescents.
• Association between Physical Activity and Mental Health in Primary School Children.
• What are the Experiences, Perceptions and Expressed Needs of Adolescents Living with Obesity and Their Mothers in Indonesia? A Qualitative Multi-Method Study.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• RCT: Integrating Executive Function Training with Health Behavior Intervention for Preschool Obesity Prevention in China.
• GLP-1 Drug Announcements and Food Sector Equity Returns: Evidence from a Structural Demand Shock.
• Sustainable Diets and Functional Foods for the Prevention of Cardio-Metabolic Diseases and Sustainable Development Goals of the UNO.
• Where You Live Shapes Diabetes Risk: Multilevel Determinants of Type 2 Diabetes in the East South Central United States.
• Global, Regional and National Intake of Plant-Based Foods Among Youth in 185 Countries (1990-2018): Findings from the Global Dietary Database.

Ethics

• Shocking ‘Leblouh’ Tradition: Fattening Farms in Mauritania, Girls Were Force-Fed Up to 10,000 Calories Per Day to Become ‘Ideal Brides’.
• Prevention of childhood obesity from a bioethical perspective.

Stigma

• Is Agreement with the Statement “Obesity Is a Disease” Helpful or Harmful? Insights from a National Cross-Sectional Survey.
• The Mediating Role of Physical Activity Avoidance in the Association between Weight Stigma and Physical Activity.
• Longitudinal Associations between Weight Self-Stigma, Physical Exercise, and Social Anxiety Among Adolescents: Between-And Within-Person Effects.

Policy Related

• Review: Integrating Policies That Enable Minimally Processed Foods with Policies That Restrict Ultra-Processed Foods for Obesity and Noncommunicable Disease Prevention.
• RCT: Eco-Focused Menu Labels on Full Meal Orders from Fast-Food Restaurants.
• Alternative Breakfast Service Models are Associated with Greater Student School Breakfast Participation. Evidence from Middle and High School Students Across 8 States.
• Out-Of-Pocket Insulin Spending Before and After the Inflation Reduction Act Across Demographic Subgroups.
• Review: Cross-Sector Policies for Achieving Equitable Obesity Prevention and Food Security.

Intergenerational Effects

• Joint Associations of Maternal Smoking and Pre-Pregnancy BMI with Term Low Birthweight and Small-For-Gestational-Age Births: A Cross-Sectional Analysis of 2024 United States Birth Data.
• Association between High Maternal Haemoglobin Levels in the First Trimester and Gestational Diabetes Mellitus: A Prospective Birth Cohort Study.
• How Maternal Diet Shapes Offspring Mitochondrial Physiology.
• Association of Iron Status with Gestational Diabetes and Preeclampsia in an Obesogenic Context: Results from a Cohort of Pregnant Chilean Women.

Ecology, Evolution, & Energetics

• The Endogenous Ghrelin Antagonist, LEAP2, Accelerates Puberty Onset in Conditions of Early Obesity.
• Capsinoids Treatment Reduces Steatosis with Consequent Attenuation in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease in Obese Rats.
• Dietary Glucoraphenin Ameliorates Obesity and Steatotic Liver Disease Associated with Gut Dysbiosis Induced by a Western Diet in Mice.
• Burgers, Brains, and Evolution: Biological and Philosophical Roots of Fat Craving.

Methods

• Systematic Review: Applications of Traditional Machine Learning and Deep Learning Algorithms in Obesity Prediction or Classification.
• An Optimized Ensemble Learning Model for Interpretable and Efficient Obesity Classification.
• Reliability and the Hidden Translational Gaps in Multidisciplinary Clinical Psychological Science.
• Integrative Multi-Omics Analysis of DNA Methylome and Transcriptome in a Tyrosine Kinase Inhibitor LPM4870108-Induced Rat Model of Obesity.

Commentary

• Podcast: No More Raw Cookie Dough with food scientist Roxi Smith.
• Podcast: GLP-1 Muscle Loss and Creatine, Bulking vs Cutting, One-Hour Training, & Detraining.
• Podcast: First RCT of Keto for Schizophrenia & Bipolar Disorder: Results & Future Directions.
• Podcast: Dietary Guidelines and the Gap in Cardio-Protective Flavanol Intake.
• Does Metabolically Healthy Obesity Really Exist: Going Toward New Definitions.
• Creatine a Supplement with a Rare Commodity: Evidence.
• Moral Panic About GLP-1s at Wimbledon.
• GLP-1s Meet Culture and Things Get Complicated.

General

• Intermittent Hypoxia Induces Reversible Epigenetic Age Acceleration in Old Mice.
• Immune Aging Biomarkers for Clinical Trials.
• Meta-Analysis: Risk Factors for the Development of Food Allergy in Infants and Children.
• JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Testosterone Therapy: Does New Evidence Warrant Broader Prescribing?"
• Genome Editing in Rats Enables More Accurate ER+ Breast Cancer Models.
• How Healthy Is Your Brain? We Now Know How to Find Out.
• Food Without Fire: Environmental and Nutritional Impacts from a Solar Stove Field Experiment.

Announcements

• Secretary Rollins Announces Growing Momentum Behind USDA’s Product of USA Label with 10 New Companies Joining Initiative.
• USDA, HHS, EPA Join Forces to Bolster Consumer Protections from Heavy Metals and Other Contaminants in Food.
• The Translational Research Institute for Space Health (TRISH) at Baylor College of Medicine Has Released a New Solicitation Seeking Proposals to Address Venous Thromboembolism (VTE), a Critical Risk to Human Health During Spaceflight.